Frosst Gillian, Hutcheon Jennifer, Joseph K S, Kinniburgh Brooke, Johnson Cathe, Lee Lily
Perinatal Services BC, West Tower, 3rd Floor, 555 West 12th Avenue, Vancouver, British Columbia, Canada, V5Z 3X7.
Department of Obstetrics and Gynaecology, University of British Columbia, Shaughnessy Building C420, BC Children's and Women's Hospital, 4500 Oak Street, Vancouver, British Columbia, Canada, V6H 3N1.
BMC Pregnancy Childbirth. 2015 May 27;15:123. doi: 10.1186/s12884-015-0563-7.
The British Columbia Perinatal Data Registry (BCPDR) contains individual-level obstetrical and neonatal medical chart data for virtually all births occurring in British Columbia, Canada. The objective of this study was to assess the validity of information in the BCPDR by performing a provincial chart re-abstraction study.
A two-stage stratified clustered sampling design was employed. Obstetrical facilities were stratified based on geographic location and obstetrical volume. Charts of mothers and newborns with a length of stay of five or more days or transfer to another facility following the delivery were oversampled. A total of 85 maternal and 32 newborn variables were assessed for completeness (percent completion) and validity (sensitivity and specificity for categorical variables, intra-class correlation coefficient [ICC] for continuous variables).
1,084 maternal and 1,142 newborn charts were abstracted. Mandatory variables such as primary indication for induction and primary indication for cesarean delivery were 100 % complete. Some variables such as pre-pregnancy weight were relatively more complete in the re-abstraction as compared with the BCPDR (83.0 % vs 76.8 %; p < 0.001). The validity of key surveillance variables was high (e.g., HIV screening completed [sensitivity 98.0 %, 95 % confidence interval (CI) 97.0-98.8 %; specificity 72.3 %, 95 % CI 60.8-81.9 %], induction of labour [sensitivity 93.9 %, 95 % CI 90.2-96.5 %; specificity 98.7 %, 95 % CI 97.7-99.3 %], primary elective cesarean delivery [sensitivity 96.0 %, 95 % CI 83.8-99.7 %; specificity 99.8 %, 95 % CI 99.4-100.0 %], gestational age from newborn examination [ICC 0.99, 95 % CI 0.99-0.99]). Examples of variables with lower validity included total admissions prior to delivery episode, maternal smoking status, and timing of breastfeeding initiation.
Many important clinical and population health variables in the BCPDR had excellent validity. Some key variables warrant strengthening through improved definitions, system changes, and abstractor training.
不列颠哥伦比亚省围产期数据登记处(BCPDR)包含了加拿大不列颠哥伦比亚省几乎所有分娩的个体层面产科和新生儿医学图表数据。本研究的目的是通过开展一项全省范围的图表重新提取研究来评估BCPDR中信息的有效性。
采用两阶段分层整群抽样设计。产科机构根据地理位置和产科工作量进行分层。对住院时间为五天或更长时间或分娩后转至另一机构的母亲和新生儿的图表进行过度抽样。共评估了85个母亲变量和32个新生儿变量的完整性(完成百分比)和有效性(分类变量的敏感性和特异性,连续变量的组内相关系数[ICC])。
提取了1084份母亲图表和1142份新生儿图表。引产的主要指征和剖宫产的主要指征等强制性变量的完整性为100%。与BCPDR相比,一些变量如孕前体重在重新提取时相对更完整(83.0%对76.8%;p<0.001)。关键监测变量的有效性较高(例如,HIV筛查完成情况[敏感性98.0%,95%置信区间(CI)97.0 - 98.8%;特异性72.3%,95%CI 60.8 - 81.9%],引产[敏感性93.9%,95%CI 90.2 - 96.5%;特异性98.7%,95%CI 97.7 - 99.3%],择期剖宫产[敏感性96.0%,95%CI 83.8 - 99.7%;特异性99.8%,95%CI 99.4 - 100.0%],新生儿检查得出的孕周[ICC 0.99,95%CI 0.99 - 0.99])。有效性较低的变量示例包括分娩前的总入院次数、母亲吸烟状况和开始母乳喂养的时间。
BCPDR中的许多重要临床和人群健康变量具有出色的有效性。一些关键变量需要通过改进定义、系统变更和提取人员培训来加强。