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伊朗人群中的代谢综合征及相关生活方式因素。

The metabolic syndrome and associated lifestyle factors among the Iranian population.

作者信息

Gharipour Mojgan, Sarrafzadegan Nizal, Sadeghi Masoumeh, Khosravi Alireza, Hoseini Mohsen, Khosravi-Boroujeni Hossein, Khaledifar Arsalan

机构信息

Department of Metabolic Syndrome, Isfahan University of Medical Sciences, Isfahan, Iran.

Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2015 May 11;4:84. doi: 10.4103/2277-9175.156645. eCollection 2015.

Abstract

BACKGROUND

This study aims to evaluate the impact of the Isfahan Healthy Heart Program (IHHP) interventions concerning healthy behavior, on the prevalence of the metabolic syndrome (MetS) and its components in the Iranian population.

MATERIALS AND METHODS

The IHHP targeted the population at large in three districts in central Iran from 2000 to 2007. Numerous interventional activities were performed to improve lifestyle. The main intervention strategies were public education through mass media, intersectional cooperation, health professional education, marketing and organizational development, legislation and policy development, as well as research and evaluation. MetS was defined based on the Adult Treatment Panel (ATP) III definition. The logistic regression method was applied to explore the relationship between lifestyle factors with components of metabolic risk factors.

RESULTS

The mean age of the participants was 44.68 ± 14.43 years in 2001. The mean values of the MetS components differed from 2001 to 2007. The mean of systolic blood pressure (SBP) decreased from 126.7 ± 22.31 to 124.21 ± 20.0 and from 129.47 ± 23.08 to 126.26 ± 21.88 among females in both the intervention and reference areas. Similar changes were observed among males. The mean diastolic blood pressure (DBP) and triglycerides decreased significantly in the intervention area and increased significantly in the reference area in both sexes. High density protein cholesterol (HDL-C) was decreased in both sexes, from 2001 to 2007, in both areas. A strong relationship between tobacco control with high SBP and hypertriglyceridemia was found (P < 0.01).

CONCLUSION

Lifestyle improvement programs could be useful to improve the MetS status among men and women.

摘要

背景

本研究旨在评估伊斯法罕健康心脏项目(IHHP)的健康行为干预措施对伊朗人群代谢综合征(MetS)及其组分患病率的影响。

材料与方法

2000年至2007年期间,IHHP针对伊朗中部三个地区的广大人群。开展了多项干预活动以改善生活方式。主要干预策略包括通过大众媒体进行公众教育、部门间合作、卫生专业人员教育、市场营销和组织发展、立法和政策制定以及研究与评估。MetS根据成人治疗小组(ATP)III定义进行定义。应用逻辑回归方法探讨生活方式因素与代谢危险因素组分之间的关系。

结果

2001年参与者的平均年龄为44.68±14.43岁。2001年至2007年期间,MetS各组分的平均值有所不同。干预区和参照区女性的收缩压(SBP)平均值分别从126.7±22.31降至124.21±20.0以及从129.47±23.08降至126.26±21.88。男性也观察到类似变化。干预区男女的舒张压(DBP)和甘油三酯显著下降,而参照区则显著上升。两个地区的男女高密度脂蛋白胆固醇(HDL-C)在2001年至2007年期间均有所下降。发现控烟与高SBP和高甘油三酯血症之间存在密切关系(P<0.01)。

结论

改善生活方式的项目可能有助于改善男性和女性的MetS状况。

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