Steinhaus Daniel A, Gainor Justin F, Vernovsky Inna, Winsett Julie, Beer Dennis J
Department of Medicine, Massachusetts General Hospital, United States.
Department of Medicine, Newton Wellesley Hospital, United States ; Division of Pulmonary Medicine, Newton Wellesley Hospital, United States.
Respir Med Case Rep. 2012 Mar 13;5:4-5. doi: 10.1016/j.rmedc.2011.12.002. eCollection 2012.
Strongyloides stercoralis is an intestinal nematode endemic to tropical and sub-tropical regions. Although infection is typically asymptomatic or self-limited, immunocompromised individuals can develop a severe form of disease marked by hyperinfection. Pulmonary involvement accompanies hyperinfection in a majority of cases, though manifestations range from asymptomatic infiltrates to diffuse alveolar hemorrhage (DAH) and respiratory failure. When complicated by DAH, the hyperinfection syndrome is usually fatal. We report a case of a 65-year-old Guatemalan woman with chronic inflammatory demyelinating polyneuropathy (CIDP) treated with chronic steroids who presented with Escherichia coli urosepsis. She was initially treated with antibiotics and corticosteroids. She subsequently developed DAH due to disseminated strongyloidiasis. She was treated with oral and subcutaneous ivermectin and had complete recovery.
粪类圆线虫是一种寄生于热带和亚热带地区的肠道线虫。虽然感染通常无症状或为自限性,但免疫功能低下的个体可能会发展为以高度感染为特征的严重疾病形式。在大多数病例中,肺部受累伴随高度感染,其表现从无症状浸润到弥漫性肺泡出血(DAH)和呼吸衰竭不等。当并发DAH时,高度感染综合征通常是致命的。我们报告一例65岁患有慢性炎症性脱髓鞘性多发性神经病(CIDP)且接受慢性类固醇治疗的危地马拉女性,她因大肠杆菌引起的泌尿道感染而就诊。她最初接受了抗生素和皮质类固醇治疗。随后,她因播散性类圆线虫病而发生DAH。她接受了口服和皮下伊维菌素治疗并完全康复。