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冠状动脉血运重建与人工关节置换术的不良事件。

Coronary revascularization and adverse events in joint arthroplasty.

机构信息

Rothman Institute of Orthopaedics, Thomas Jefferson University, Philadelphia, Pennsylvania.

Rothman Institute of Orthopaedics, Thomas Jefferson University, Philadelphia, Pennsylvania.

出版信息

J Surg Res. 2015 Sep;198(1):135-42. doi: 10.1016/j.jss.2015.05.013. Epub 2015 May 14.

Abstract

BACKGROUND

There is a paucity of literature about outcome of total joint arthroplasty in patients with the history of angioplasty and/or stent or coronary artery bypass graft (CABG). The present study aimed to evaluate perioperative complications and mortality in these patients.

METHODS

We used the Nationwide Inpatient Sample data from 2002-2011. Using the Ninth Revision of the International Classification of Disease, Clinical Modification codes for disorders and procedures, we identified patients with a history of coronary revascularization (angioplasty and/or stent or CABG) and compared the inhospital adverse events in these patients with patients without a history of coronary revascularization.

RESULTS

Cardiac complications occurred in 1.06% patients with a history of CABG; 0.95% of patients with a coronary angioplasty and/or stent and 0.82% of the control patients. In the multivariate analysis, neither the history of CABG (P = 0.07) nor the history of angioplasty and/or stenting (P = 0.86) was associated with a higher risk of cardiac complications. However, myocardial infarction occurred in a significantly higher proportion of patients with the history of CABG (0.66%, odds ratio, 1.24, P = 0.001) and coronary angioplasty and/or stenting (0.67%, odds ratio, 1.96, P < 0.001) compared with that in the controls (0.27%). History of coronary revascularization did not increase the risk of respiratory, renal, and wound complications, surgical site infection, and mortality.

CONCLUSIONS

Based on the findings of this study, it appears that there is no increased risk of inhospital mortality and complications (except for myocardial infarction) in patients with a history of coronary artery revascularization undergoing total joint arthroplasty. We also found perioperative cardiac arrhythmia, particularly atrial fibrillation, to be an independent predictor of inhospital adverse events.

摘要

背景

关于有经皮冠状动脉介入治疗(PCI)史和/或支架或冠状动脉旁路移植术(CABG)史的患者行全关节置换术的结局,文献报道较少。本研究旨在评估这些患者的围手术期并发症和死亡率。

方法

我们使用了 2002-2011 年全国住院患者样本数据。使用国际疾病分类第 9 版修订版(ICD-9-CM)疾病和操作的临床修正代码,我们确定了有冠状动脉血运重建(PCI 和/或支架或 CABG)史的患者,并比较了这些患者与无冠状动脉血运重建史患者的院内不良事件。

结果

CABG 史患者的心脏并发症发生率为 1.06%;有 PCI 和/或支架史的患者为 0.95%,对照组为 0.82%。多变量分析显示,CABG 史(P=0.07)或 PCI 和/或支架史(P=0.86)均与更高的心脏并发症风险无关。然而,与对照组(0.27%)相比,CABG 史(0.66%,优势比 1.24,P=0.001)和 PCI 和/或支架史(0.67%,优势比 1.96,P<0.001)患者的心肌梗死发生率显著更高。冠状动脉血运重建史并未增加呼吸系统、肾脏和伤口并发症、手术部位感染和死亡率的风险。

结论

根据本研究的结果,似乎有冠状动脉血运重建史的患者行全关节置换术并没有增加院内死亡率和并发症(心肌梗死除外)的风险。我们还发现,围手术期的心律失常,特别是心房颤动,是院内不良事件的独立预测因素。

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