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早期插管式人工血管移植物(Acuseal™)在血液透析血管通路中的应用。

The use of the early cannulation prosthetic graft (Acuseal™) for angioaccess for haemodialysis.

作者信息

Maytham Gary G D, Sran H K, Chemla Eric S

机构信息

Vascular Institute, St George's Healthcare NHS Trust, London - UK.

出版信息

J Vasc Access. 2015 Nov-Dec;16(6):467-71. doi: 10.5301/jva.5000390. Epub 2015 May 23.

Abstract

OBJECTIVES

Autogenous arteriovenous (AV) accesses are the preferred choice for the delivery of haemodialysis (HD). With an increase in the prevalence of end-stage renal disease and in the life expectancy of these patients, the quality and availability of superficial vessels can be limited and reduced with time. The use of prosthetic AV accesses may therefore become necessary for the delivery of HD. A new early cannulation vascular prosthesis (GORE® ACUSEAL Vascular Graft) has been introduced, developed to hinder suture line and cannulation needle bleeding. The authors report their experience with this new conduit at a London teaching hospital.

METHODS

Between May 2011 and June 2013, 52 patients underwent 55 procedures where the ACUSEAL® prosthetic AV access was utilized to facilitate HD. The majority of procedures involved the placement of prosthetic brachio-axillary accesses or prosthetic axillo-axillary chest accesses.

RESULTS

The 1-year primary and secondary patency was found to be 46% and 61%, respectively. Successful cannulation of the newly placed AV access was performed with 24 hours of surgery in 40 patients (73%). Tunnelled vascular catheters were required in only 10 (18%) patients. Six (11%) of the patients in the study suffered early complications, and 9 (16%) patients developed AV access infection.

CONCLUSIONS

These results show that, while providing patency results that compare favourably to those published for other types of regular prosthetic accesses, the conduits are amenable to very early cannulation with few cannulation-related complications. This leads to a dramatic reduction in the need for temporary or tunnelled catheters.

摘要

目的

自体动静脉内瘘是血液透析(HD)的首选通路。随着终末期肾病患病率的上升以及这些患者预期寿命的延长,浅表血管的质量和可用性可能会随着时间的推移而受到限制并降低。因此,使用人工血管动静脉内瘘进行血液透析可能变得必要。一种新型的早期插管血管假体(戈尔®ACUSEAL血管移植物)已被引入,其设计目的是减少缝合线和插管针处的出血。作者报告了他们在伦敦一家教学医院使用这种新型导管的经验。

方法

2011年5月至2013年6月期间,52例患者接受了55次手术,使用ACUSEAL®人工血管动静脉内瘘来辅助血液透析。大多数手术涉及放置人工肱腋内瘘或人工腋腋胸部内瘘。

结果

1年的初级和次级通畅率分别为46%和61%。40例患者(73%)在手术后24小时内成功对新放置的动静脉内瘘进行了插管。仅10例(18%)患者需要使用隧道式血管导管。研究中的6例(11%)患者出现早期并发症,9例(16%)患者发生动静脉内瘘感染。

结论

这些结果表明,虽然该导管的通畅率与其他类型的常规人工血管通路相比具有优势,但它适合早期插管,且插管相关并发症较少。这导致对临时或隧道式导管的需求大幅减少。

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