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先天性大便失禁股薄肌成形术中两种不同的股薄肌袢:治疗效果比较

Two different gracilis loops in graciloplasty of congenital fecal incontinence: comparison of the therapeutic effects.

作者信息

Shi Gang-Gang, Wang Hui, Wang Li, Zhang Zuo-Xing, Wang Hao

机构信息

Department of Colorectal Surgery, The Second Hospital of Tianjin Medical University, Tianjin, China.

Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

Int J Colorectal Dis. 2015 Oct;30(10):1391-7. doi: 10.1007/s00384-015-2274-y. Epub 2015 Jun 18.

Abstract

PURPOSE

The aim of this study was to compare the clinical effect of graciloplasty using two different gracilis encircled loops for the treatment of fecal incontinence after anoplasty for imperforate anus.

METHODS

From January 2009 to January 2012, 38 patients were treated by graciloplasty. The patients were randomly divided into two groups, one group consisting of 18 cases underwent the "γ-loop" and the other group consisting of 20 cases underwent the "υ-loop." All patients underwent postoperative defecation training and regular follow-up. All patients were evaluated via Wexner score and anal manometry (including anal resting pressure, anal maximal squeeze pressure, duration of anal squeeze, and rectal maximum tolerable volume) before and after graciloplasty. In addition, it was assessed whether the patients had difficulty defecating while squatting after surgery.

RESULTS

The surgeries on the 38 patients were accomplished successfully. There were no differences in postoperative complications between the two groups (P > 0.05). The Wexner score and anal manometry parameters of the two groups were gradually improved after operation. The generalized estimating equation results of the Wexner score indicated that the difference of measurement time was statistically significant (P < 0.05) but the difference of measurement group was not statistically significant (P > 0.05). The results of anal manometry parameters using repeated measures ANOVA indicated that differences between different time points were statistically significant (all P < 0.05) but differences between different surgery groups were not statistically significant (all P > 0.05). Regarding the postoperative defecating difficulties while squatting, the probability of occurrence in the "γ-loop" group was significantly higher than that in the "υ-loop" group. The difference between the two groups was statistically significant (P < 0.05).

CONCLUSIONS

Graciloplasty with different gracilis loops can improve anal function in patients. However, "υ-loop" can significantly improve difficulties in defecating while squatting.

摘要

目的

本研究旨在比较采用两种不同股薄肌环绕袢行股薄肌成形术治疗肛门闭锁肛门成形术后大便失禁的临床效果。

方法

2009年1月至2012年1月,38例患者接受股薄肌成形术治疗。患者被随机分为两组,一组18例行“γ袢”手术,另一组20例行“υ袢”手术。所有患者术后均接受排便训练并定期随访。所有患者在股薄肌成形术前和术后均通过Wexner评分和肛门测压法(包括肛门静息压、肛门最大收缩压、肛门收缩持续时间和直肠最大耐受容量)进行评估。此外,评估患者术后蹲位排便时是否有排便困难。

结果

38例患者手术均成功完成。两组术后并发症无差异(P>0.05)。两组术后Wexner评分和肛门测压参数均逐渐改善。Wexner评分的广义估计方程结果表明,测量时间差异有统计学意义(P<0.05),但测量组差异无统计学意义(P>0.05)。采用重复测量方差分析的肛门测压参数结果表明,不同时间点之间的差异有统计学意义(所有P<0.05),但不同手术组之间的差异无统计学意义(所有P>0.05)。关于术后蹲位排便困难,“γ袢”组的发生率显著高于“υ袢”组。两组之间的差异有统计学意义(P<0.05)。

结论

采用不同股薄肌袢的股薄肌成形术可改善患者肛门功能。然而,“υ袢”可显著改善蹲位排便困难。

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