Rezar Sandra, Sacu Stefan, Blum Robert, Eibenberger Katharina, Schmidt-Erfurth Ursula, Georgopoulos Michael
a Department of Ophthalmology and Optometry , Medical University of Vienna , Vienna , Austria.
Curr Eye Res. 2016 Apr;41(4):543-50. doi: 10.3109/02713683.2015.1031351. Epub 2015 Jun 17.
To evaluate anatomical and functional outcomes of macula-on and macula-off rhegmatogenous retinal detachment (RRD) after 23-gauge vitrectomy and gas endotamponade, in eyes after successful cataract surgery.
Forty-six pseudophakic eyes of 46 consecutive patients who underwent surgery for RRD repair were included. Based on the severity degree and extension of the RRD, diluted C3F8, SF6 or C2F6 gases were used for endotamponade. Patients were followed 1 month, 3 months, 6 months and 12 months after surgery. Main outcome variables were functional and anatomic outcomes till 12 months after surgery.
Proliferative vitreoretinopathy of grade B or C was observed in 43%. C3F8 was used in 59%, SF6 in 28% and C2F6 in 13%. Reattachment after the first intervention was achieved in 89%. Preoperatively, 63% of patients presented with fovea-off retinal detachment. No intraoperative complications were registered. Preoperatively, eyes with macula-on RRD had a logMar BCVA of 0.3 ± 0.6 compared with 1.2 ± 0.7 in the macula-off group (p = 0.01). The mean visual acuity significantly improved to 0.06 ± 0.1 logMar in macula-on eyes and to 0.2 ± 0.3 logMar in macula-off eyes at 12 months (p = 0.01 compared to baseline and p = 0.04 between both the groups). The mean final postoperative CRT was 318 ± 48 µm in the macula-on group compared with 305 ± 71 µm in the macula-off group (p = 0.5).
Even morphological improvement after 23-gauge vitrectomy and gas endotamponade was comparable between macula-on and macula-off eyes, macula-off RRDs showed delayed visual rehabilitation. Both groups showed significant visual acuity improvement until 12 months, however, macula-on RRDs showed significantly more improvement than macula-off RRDs.
评估成功进行白内障手术后,23G玻璃体切除联合气体内填充治疗黄斑在位和黄斑脱离的孔源性视网膜脱离(RRD)的解剖和功能结局。
纳入46例连续接受RRD修复手术患者的46只人工晶状体眼。根据RRD的严重程度和范围,使用稀释的C3F8、SF6或C2F6气体进行内填充。术后1个月、3个月、6个月和12个月对患者进行随访。主要结局变量为术后12个月内的功能和解剖结局。
观察到43%的患者发生B级或C级增生性玻璃体视网膜病变。59%的患者使用C3F8,28%使用SF6,13%使用C2F6。首次干预后视网膜复位率为89%。术前,63%的患者表现为黄斑脱离性视网膜脱离。未记录到术中并发症。术前,黄斑在位RRD患者的logMar最佳矫正视力(BCVA)为0.3±0.6,而黄斑脱离组为1.2±0.7(p = 0.01)。12个月时,黄斑在位眼的平均视力显著提高至0.06±0.1 logMar,黄斑脱离眼提高至0.2±0.3 logMar(与基线相比p = 0.01,两组间p = 0.04)。黄斑在位组术后平均最终中央视网膜厚度(CRT)为318±48 µm,黄斑脱离组为305±71 µm(p = 0.5)。
尽管23G玻璃体切除联合气体内填充后黄斑在位和黄斑脱离眼的形态学改善相当,但黄斑脱离的RRD显示视觉康复延迟。两组在12个月时视力均有显著改善,但黄斑在位的RRD改善明显多于黄斑脱离的RRD。