Gao X, Huang K-P, Wu H-Y, Sun P-P, Yan J-J, Chen J, Chen X
Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
J Clin Pharm Ther. 2015 Oct;40(5):489-495. doi: 10.1111/jcpt.12295. Epub 2015 Jun 11.
It is known that mismanagement of intravenous (IV) fluid therapy may cause serious complications. The 2013 NICE guideline on intravenous fluid therapy in hospitalized adults also emphasizes the importance of appropriate prescribing of IV fluid. So far, no systematic review of the incidence and types of inappropriate prescribing of IV fluid has been conducted. Therefore, this study was undertaken to review the research literature on inappropriate prescribing of IV fluid in adult patients and develop corresponding strategies for improving practice.
A comprehensive literature search was performed. Critical appraisals were conducted on the articles drawn from the search, and an analysis was performed on the results.
Incorrect volumes and types of IV fluids prescribed, classified as misprescribing, was the most common type of inappropriate prescribing. Commonly, patients on IV fluid therapy were prescribed a greater volume of fluid and amount of sodium in excess of normal requirements. Doctors did not always check the body weight, serum electrolyte level and serum creatinine before prescribing IV fluid for patients. The other common type of inappropriate prescribing was incomplete/incorrect prescription writing. These common inappropriate prescribing of IV fluid could be caused by insufficient knowledge and training of the prescribers. In addition, the ignorance of the importance of IV fluid prescribing also contributed to this behaviour.
There is an urgent need to make doctors aware of these problems and enhance appropriate training on IV fluid prescribing, especially on the appropriate volume and amount of electrolytes. Pharmacists could exert a role in reviewing the fluid prescription chart for improving clinical practice.
众所周知,静脉输液治疗管理不当可能会导致严重并发症。2013年英国国家卫生与临床优化研究所(NICE)关于成人住院患者静脉输液治疗的指南也强调了合理开具静脉输液处方的重要性。到目前为止,尚未对静脉输液不合理处方的发生率和类型进行系统综述。因此,本研究旨在回顾关于成人患者静脉输液不合理处方的研究文献,并制定相应的改进措施。
进行了全面的文献检索。对检索到的文章进行了严格评价,并对结果进行了分析。
静脉输液处方的量和类型错误(归类为处方错误)是最常见的不合理处方类型。通常,接受静脉输液治疗的患者所开具的液体量和钠含量超过正常需求量。医生在为患者开具静脉输液处方前并不总是检查患者的体重、血清电解质水平和血清肌酐。另一种常见的不合理处方类型是处方书写不完整/错误。这些常见的静脉输液不合理处方可能是由于开处方者知识不足和培训不够造成的。此外,对静脉输液处方重要性的忽视也导致了这种行为。
迫切需要让医生意识到这些问题,并加强关于静脉输液处方的适当培训,特别是关于适当的液体量和电解质含量。药剂师可以在审查输液处方表以改善临床实践方面发挥作用。