B-1细胞发育中的核因子-κB信号传导
NF-κB signaling in B-1 cell development.
作者信息
Pedersen Gabriel K, Ádori Monika, Karlsson Hedestam Gunilla B
机构信息
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
出版信息
Ann N Y Acad Sci. 2015 Dec;1362:39-47. doi: 10.1111/nyas.12800. Epub 2015 Jun 11.
PMID:26096766
Abstract
NF-κB transcription factors play essential roles in hematopoiesis. In this review, we summarize the requirements of different components of the NF-κB pathway for B-1 cell development and maintenance. The B-1 cell developmental steps are also reviewed, with particular emphasis on stages where NF-κB signaling may be critical.
摘要
核因子-κB转录因子在造血过程中发挥着至关重要的作用。在本综述中，我们总结了核因子-κB信号通路不同组分对B-1细胞发育和维持的需求。我们还对B-1细胞的发育步骤进行了综述，特别强调了核因子-κB信号可能起关键作用的阶段。
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