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成釉细胞瘤的氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)表现:一例报告

FDG-PET findings of Ameloblastoma: a case report.

作者信息

Seno Satoshi, Kitajima Kazuhiro, Inokuchi Go, Nibu Ken-Ichi, Itoh Tomoo, Ejima Yasuo, Sasaki Ryohei, Sugimoto Koji, Sugimura Kazuro

机构信息

Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017 Japan.

Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017 Japan.

出版信息

Springerplus. 2015 Jun 11;4:250. doi: 10.1186/s40064-015-0998-3. eCollection 2015.

Abstract

INTRODUCTION

Ameloblastoma is a benign odontogenic neoplasm of the jaw, rarely presenting as a malignant tumor. Although it is very important to discriminate ameloblastoma from ameloblastic carcinoma in order to decide the appropriate operative procedure, this is difficult using conventional CT and MRI.

CASE DESCRIPTIONS

We report a case of maxillar ameloblastoma in a 78-year-old man where FDG-PET/CT was useful for making this discrimination. CT demonstrated a 31 × 43 × 46-mm mass in the left posterior maxillary sinus with destruction of its posterior and lateral wall and alveolar bone. MRI demonstrated a hypo- to isointense heterogeneous pattern on T1WI, heterogeneous hyperintensity with a prominent high-signal spot on T2WI, high signal intensity on DWI reflecting restricted diffusion, and strong heterogeneous enhancement. Because FDG-PET/CT showed mild FDG uptake (SUVmax 2.40) by the mass, ameloblastoma, rather than ameloblastic carcinoma, was considered to be the correct diagnosis.

DISCUSSION AND EVALUATION

It appears that ameloblastic carcinoma shows intense FDG uptake, whereas ameloblastoma shows mild or moderate FDG uptake, and only rarely intense FDG uptake. Our experience suggests that FDG-PET/CT may be effective for discriminating ameloblastoma from ameloblastic carcinoma. Especially, in cases showing mild FDG uptake, benign ameloblastoma would seem the most likely diagnosis.

CONCLUSIONS

FDG-PET/CT may be useful as an adjunctive modality for diagnosis, treatment planning and surveillance of ameloblastoma and ameloblastic carcinoma.

摘要

引言

成釉细胞瘤是颌骨的一种良性牙源性肿瘤,很少表现为恶性肿瘤。尽管为了确定合适的手术方式,将成釉细胞瘤与成釉细胞癌区分开来非常重要,但使用传统的CT和MRI很难做到这一点。

病例描述

我们报告一例78岁男性上颌骨成釉细胞瘤病例,其中FDG-PET/CT有助于做出这种区分。CT显示左上颌窦后部有一个31×43×46mm的肿块,其后壁和外侧壁以及牙槽骨破坏。MRI显示T1WI上呈低至等信号不均匀模式,T2WI上呈不均匀高信号,有一个明显的高信号点,DWI上呈高信号强度反映扩散受限,增强扫描呈强烈不均匀强化。由于FDG-PET/CT显示该肿块有轻度FDG摄取(SUVmax 2.40),因此考虑正确诊断为成釉细胞瘤而非成釉细胞癌。

讨论与评价

成釉细胞癌似乎显示出强烈的FDG摄取,而成釉细胞瘤显示出轻度或中度FDG摄取,仅极少数情况下显示强烈FDG摄取。我们的经验表明,FDG-PET/CT可能有助于将成釉细胞瘤与成釉细胞癌区分开来。特别是在显示轻度FDG摄取的病例中,良性成釉细胞瘤似乎是最可能的诊断。

结论

FDG-PET/CT可能作为一种辅助手段用于成釉细胞瘤和成釉细胞癌的诊断、治疗计划制定及监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79f5/4474970/5baa4e3cb6fb/40064_2015_998_Fig1_HTML.jpg

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