Seguchi H, Yagyu Y, Kobayashi T
Department of Anatomy, Kochi Medical School, Nankoku, Japan.
Anat Anz. 1989;169(4):225-34.
The nerve endings of normal hair of the rat's snout, partially digested with trypsin and hydrochloric acid, were studied by scanning electron microscopy. Each lanceolate structure measured ca. 10 microns in length and was arranged around the hair follicle. These palisade-shaped nerve endings were situated almost beneath the sebaceous glands, ran upward, parallel to the axis of the hair follicle, and terminated in pointed shape. 2 kinds of cells, Teloglia cell Type I showing flat profile, and Teloglia cell Type II showing spherical profile and possessing numerous caveolae in its surface were observed at the basal portion of the palisade-shaped endings. The axon was enclosed by Schwann cells in its course to the hair follicle, and was covered with Type I cells at the beginning, and with Type II cells at the end, and constituted the palisade-shaped nerve endings. The palisade structure in silver impregnated tissues observed by backscattered electron microscopy and X-ray analyzer was characterized as comprising neuronal elements. Cytochemically, the nerve endings showed cholinesterase and Mg-ATPase activities. They may be involved in the reception of the mechanical stimulation of the hair. The palisade nerve endings thus possessed appropriate 3-dimensional structure as mechanoreceptor.
用扫描电子显微镜研究了经胰蛋白酶和盐酸部分消化的大鼠吻部正常毛发的神经末梢。每个矛状结构长度约为10微米，围绕毛囊排列。这些栅栏状神经末梢几乎位于皮脂腺下方，向上平行于毛囊轴延伸，并呈尖状终止。在栅栏状末梢的基部观察到两种细胞，I型终末神经胶质细胞呈扁平状，II型终末神经胶质细胞呈球状，其表面有许多小窝。轴突在向毛囊的行程中被施万细胞包裹，起始处被I型细胞覆盖，末端被II型细胞覆盖，构成栅栏状神经末梢。通过背散射电子显微镜和X射线分析仪观察到的银浸染组织中的栅栏状结构，其特征是包含神经元成分。细胞化学研究表明，神经末梢具有胆碱酯酶和Mg - ATP酶活性。它们可能参与毛发机械刺激的感受。因此，栅栏状神经末梢具有作为机械感受器的合适三维结构。
