Kim Ji Heui, Lee Yoon Se, Chung Yoo-Sam, Jang Yong Ju, Kim Sung-Bae, Lee Sang-Wook, Lee Bong-Jae
a 1 Department of Otolaryngology.
b 2 Department of Oncology.
Acta Otolaryngol. 2015;135(11):1189-95. doi: 10.3109/00016489.2015.1061697. Epub 2015 Jun 25.
CCRT is a potential treatment option for locally advanced sinonasal SCC in terms of organ preservation.
Concurrent chemoradiotherapy (CCRT) is increasingly used for patients with advanced head and neck cancer to preserve organ function and improve survival. In the present study, treatment outcomes were compared between surgery and post-operative radiotherapy (PORT) and CCRT in patients with locally advanced sinonasal squamous cell carcinoma (SCC).
The records of 30 patients with non-metastatic stage III and IV sinonasal SCC were retrospectively reviewed. Fifteen patients were treated with CCRT and 15 patients underwent PORT.
The locoregional recurrence-free, distant metastasis-free, disease-free, disease-specific, and overall survival rates did not differ between PORT and CCRT groups. In addition, there were no significant differences in incidence rates of acute and chronic toxicities between the two groups.
就器官保留而言，同步放化疗是局部晚期鼻窦鳞状细胞癌的一种潜在治疗选择。
同步放化疗（CCRT）越来越多地用于晚期头颈癌患者以保留器官功能并提高生存率。在本研究中，比较了局部晚期鼻窦鳞状细胞癌（SCC）患者接受手术及术后放疗（PORT）与CCRT的治疗结果。
回顾性分析30例非转移性III期和IV期鼻窦SCC患者的记录。15例患者接受CCRT治疗，15例患者接受PORT治疗。
PORT组和CCRT组之间的局部区域无复发生存率、无远处转移生存率、无病生存率、疾病特异性生存率和总生存率无差异。此外，两组之间急慢性毒性发生率也无显著差异。
