一次意外发现：一例因服用神圣泻药导致急性肝损伤后偶然发现的胆管癌病例。
A Serendipitous Find: A Case of Cholangiocarcinoma Identified Incidentally After Acute Liver Injury Due to Cascara sagrada Ingestion.
作者信息
Nakasone Elizabeth S, Tokeshi Jinichi
机构信息
John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI.
出版信息
Hawaii J Med Public Health. 2015 Jun;74(6):200-2.
Abstract
The use of anthranoid laxatives such as Cascara sagrada can, in rare instances, produce a hepatitis that resolves with discontinuation of the offending supplement. However, the clinical presentation of abdominal pain, jaundice, clay-colored stools, and darkening urine can mimic the presentation of a variety of hepatobiliary illnesses, including cholangiocarcinoma. This case report describes a local patient diagnosed with an extrahepatic cholangiocarcinoma following workup for an acute hepatitis due to ingestion of large quantities of Cascara sagrada.
摘要
使用诸如美鼠李皮等蒽醌类泻药在极少数情况下可能会引发肝炎，停用相关补充剂后肝炎会消退。然而，腹痛、黄疸、陶土样大便和尿液颜色加深等临床表现可能与包括胆管癌在内的多种肝胆疾病的表现相似。本病例报告描述了一名本地患者，因大量摄入美鼠李皮导致急性肝炎，经检查后被诊断为肝外胆管癌。
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