Catheterization Laboratory and Cardiovascular Interventional Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Catheterization Laboratory and Cardiovascular Interventional Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, Tunisia.
Can J Cardiol. 2015 Aug;31(8):974-9. doi: 10.1016/j.cjca.2015.03.001. Epub 2015 Mar 5.
Chronic total occlusions (CTOs) represent a common lesion subset observed in patients who undergo coronary angiography. During the past decade, the interest of the interventionist community in CTOs has exponentially grown with fast advancement in dedicated equipment and techniques, which has resulted in high rates of procedural success and low rates of complications. Although different observational studies have shown that CTO revascularization was associated with good clinical outcome, its real benefit for patients remains to be determined, particularly in the absence of randomized trials. In addition, compared with non-CTO lesions, the American and European guidelines downgraded percutaneous coronary intervention in the setting of CTOs. In this viewpoint, we try to identify patients who would benefit from CTO recanalization, and discuss the issues that might improve the appropriateness of CTO percutaneous coronary intervention.
慢性完全闭塞病变(CTO)是指在接受冠状动脉造影的患者中观察到的常见病变亚型。在过去的十年中,随着专用设备和技术的快速发展,介入医生对 CTO 的兴趣呈指数级增长,这导致了较高的手术成功率和较低的并发症发生率。尽管不同的观察性研究表明 CTO 血运重建与良好的临床结局相关,但它对患者的实际益处仍有待确定,特别是在缺乏随机试验的情况下。此外,与非 CTO 病变相比,美国和欧洲指南降低了 CTO 病变时经皮冠状动脉介入治疗的推荐级别。在本观点中,我们试图确定哪些患者将从 CTO 再通中获益,并讨论可能提高 CTO 经皮冠状动脉介入治疗适宜性的问题。