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经皮再通术治疗混合型布加综合征:策略与长期疗效

Percutaneous recanalization for combined-type Budd-Chiari syndrome: strategy and long-term outcome.

作者信息

Fu Yu-Fei, Li Yu, Cui Yan-Feng, Wei Ning, Li De-Chun, Xu Hao

机构信息

Department of Radiology, Xuzhou Central Hospital, 199 South Jie-fang Road, Xuzhou, 221009, China.

Department of Interventional Radiology, The Affiliated Hospital of Xuzhou Medical College, 99 West Huai-hai Road, Xuzhou, 221006, China.

出版信息

Abdom Imaging. 2015 Oct;40(8):3240-7. doi: 10.1007/s00261-015-0496-7.

Abstract

PURPOSE

To investigate the feasibility, strategy, and long-term outcome of percutaneous recanalization for combined-type Budd-Chiari syndrome (BCS).

METHODS

From December 2007 to August 2014, consecutive symptomatic combined-type BCS patients were treated by percutaneous recanalization in our centers. Inferior vena cava (IVC) recanalization was the first-stage treatment for all patients. Recanalization of one hepatic vein (HV) was the second-stage treatment for the selected patients. If the patient had the compensatory and patent accessory HV (AHV), we observed this patient for 7 days after IVC recanalization. If the symptoms of portal hypertension improved, HV recanalization was not needed. Otherwise, HV recanalization was performed. If the patient had no patent AHV, HV recanalization was performed 3 days after IVC recanalization. Data on technical success, clinical success, and follow-up were analyzed, respectively.

RESULTS

Sixty-two symptomatic combined-type BCS patients were enrolled. Technical success of percutaneous recanalization was achieved in 60 patients. Among them, 52 patients had the patent AHV and underwent single IVC recanalization, and 8 patients had no patent AHV and underwent combined IVC and HV recanalization. Clinical success was achieved in all of the 60 patients. Three patients died during the follow-up. The cumulative 1-, 2-, and 4-year survival rates were 98.3%, 96.5%, and 92.7%, respectively.

CONCLUSION

Percutaneous recanalization is suitable for most combined-type BCS patients. Treatment strategy can be made according to the situation of AHV. If the patient has the patent AHV, single IVC recanalization is enough. Otherwise, combined IVC and HV recanalization should be performed.

摘要

目的

探讨经皮再通术治疗混合型布加综合征(BCS)的可行性、策略及长期疗效。

方法

2007年12月至2014年8月,在我们中心对连续性有症状的混合型BCS患者采用经皮再通术治疗。下腔静脉(IVC)再通是所有患者的第一阶段治疗。对部分患者进行一条肝静脉(HV)再通作为第二阶段治疗。若患者有代偿性且通畅的副肝静脉(AHV),在IVC再通后观察7天。若门静脉高压症状改善,则无需进行HV再通。否则,进行HV再通。若患者无通畅的AHV,则在IVC再通后3天进行HV再通。分别分析技术成功率、临床成功率及随访数据。

结果

纳入62例有症状的混合型BCS患者。60例患者经皮再通术获得技术成功。其中,52例患者有通畅的AHV,仅接受了IVC再通,8例患者无通畅的AHV,接受了IVC和HV联合再通。60例患者均获得临床成功。3例患者在随访期间死亡。1年、2年和4年的累积生存率分别为98.3%、96.5%和92.7%。

结论

经皮再通术适用于大多数混合型BCS患者。可根据AHV情况制定治疗策略。若患者有通畅的AHV,单纯IVC再通即可。否则,应进行IVC和HV联合再通。

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