碘盐普及时代后斯里兰卡的甲状腺肿流行病学
Epidemiology of goitre in Sri Lanka in the post-iodization era.
作者信息
Fernando R, Pathmeswaran A, Pinto M D P
机构信息
Departments of Surgery, University of Kelaniya, Sri Lanka.
出版信息
Ceylon Med J. 2015 Jun;60(2):41-4. doi: 10.4038/cmj.v60i2.8150.
INTRODUCTION
Previous studies of goitre in Sri Lanka proposed the presence of a goitre belt, which was refuted subsequently. Epidemiology of goitre in the post iodization era needs re-evaluation. Objectives To describe the epidemiology of goitre in Sri Lanka.
METHODS
A descriptive cross-sectional study was conducted in designated zones except in conflict areas in 2006/2007. An interviewer administered questionnaire was used and patients were evaluated clinically, biochemically and cytologically.
RESULTS
Among 5200 participans 426 had goitre. Mean age was 36.3 (SD 17.3) years. Goitre was commonest in the age group 40-49 years with a female pre-ponderance. The prevalence was similar in all zones with pockets of high prevalence in each zone. Overall islandwide adjusted prevalence was 6.8% (95% CI = 6.0-7.6).
CONCLUSIONS
There was no identifiable goitre belt.There were pockets of high prevalence in all zones. Goitre remains a public health issue despite universal iodization.
引言
此前关于斯里兰卡甲状腺肿的研究提出存在一个甲状腺肿带，但该观点随后遭到驳斥。碘盐普及时代后的甲状腺肿流行病学需要重新评估。目的是描述斯里兰卡甲状腺肿的流行病学情况。
方法
2006/2007年在除冲突地区外的指定区域开展了一项描述性横断面研究。使用了由访谈员填写的问卷，并对患者进行了临床、生化和细胞学评估。
结果
在5200名参与者中，426人患有甲状腺肿。平均年龄为36.3岁（标准差17.3）。甲状腺肿在40 - 49岁年龄组最为常见，女性居多。所有区域的患病率相似，每个区域都有高患病率的局部地区。全岛经调整后的总体患病率为6.8%（95%置信区间 = 6.0 - 7.6）。
结论
不存在可识别的甲状腺肿带。所有区域都有高患病率的局部地区。尽管普遍食用碘盐，但甲状腺肿仍然是一个公共卫生问题。
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