James Andrew I W, Böhnke Jan R, Young Andrew W, Lewis Gary J
Proc Biol Sci. 2015 Jul 22;282(1811). doi: 10.1098/rspb.2015.0711.
Understanding the underpinnings of behavioural disturbances following brain injury is of considerable importance, but little at present is known about the relationships between different types of behavioural disturbances. Here, we take a novel approach to this issue by using confirmatory factor analysis to elucidate the architecture of verbal aggression, physical aggression and inappropriate sexual behaviour using systematic records made across an eight-week observation period for a large sample (n = 301) of individuals with a range of brain injuries. This approach offers a powerful test of the architecture of these behavioural disturbances by testing the fit between observed behaviours and different theoretical models. We chose models that reflected alternative theoretical perspectives based on generalized disinhibition (Model 1), a difference between aggression and inappropriate sexual behaviour (Model 2), or on the idea that verbal aggression, physical aggression and inappropriate sexual behaviour reflect broadly distinct but correlated clinical phenomena (Model 3). Model 3 provided the best fit to the data indicating that these behaviours can be viewed as distinct, but with substantial overlap. These data are important both for developing models concerning the architecture of behaviour as well as for clinical management in individuals with brain injury.
了解脑损伤后行为障碍的潜在机制具有相当重要的意义,但目前对于不同类型行为障碍之间的关系知之甚少。在此,我们采用一种新颖的方法来解决这个问题,即使用验证性因素分析,通过对大量(n = 301)患有各种脑损伤的个体在八周观察期内进行的系统记录,来阐明言语攻击、身体攻击和不当性行为的结构。这种方法通过测试观察到的行为与不同理论模型之间的拟合度,对这些行为障碍的结构进行了有力的检验。我们选择了基于广义去抑制(模型1)、攻击与不当性行为之间的差异(模型2)或言语攻击、身体攻击和不当性行为反映广泛不同但相关的临床现象这一观点(模型3)的模型,这些模型反映了不同的理论观点。模型3与数据的拟合度最佳,表明这些行为可以被视为不同的,但有大量重叠。这些数据对于建立行为结构模型以及脑损伤个体的临床管理都很重要。