采用印度大动脉炎临床活动评分对大动脉炎患者进行常规评估。
Assessment of Patients with Takayasu Arteritis in Routine Practice with Indian Takayasu Clinical Activity Score.
作者信息
Alibaz-Oner Fatma, Aydin Sibel Z, Akar Servet, Aksu Kenan, Kamali Sevil, Yucel Eftal, Karadag Omer, Ozer Huseyin, Kiraz Sedat, Onen Fatos, Inanc Murat, Keser Gokhan, Akkoc Nurullah, Direskeneli Haner
机构信息
From the Department of Rheumatology Istanbul, School of Medicine, Marmara University; Department of Rheumatology, Koç University; Department of Rheumatology, Faculty of Medicine, Istanbul University, Istanbul; Department of Rheumatology, School of Medicine, Dokuz Eylul University; Department of Rheumatology, School of Medicine, Ege University, İzmir; Department of Rheumatology, School of Medicine, Baskent University; Department of Rheumatology, School of Medicine, Hacettepe University, Ankara, Turkey; Department of Rheumatology, School of Medicine, Cukurova University, Adana, Turkey.F. Alibaz-Oner, MD, Specialist in Rheumatology, Department of Rheumatology, School of Medicine, Marmara University; S.Z. Aydin, MD, Associate Professor of Rheumatology, Department of Rheumatology, Koç University; S. Akar, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine, Dokuz Eylul University; K. Aksu, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine, Ege University; S. Kamali, MD, Professor of Rheumatology, Department of Rheumatology, Faculty of Medicine, Istanbul University;E. Yucel, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine, Baskent University; O. Karadag, MD, Associate Professor of Rheumatology, Department of Rheumatology, School of Medicine, Hacettepe University; H. Ozer, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine, Cukurova University; S. Kiraz, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine, Hacettepe University; F. Onen, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine, Dokuz Eylul University; M. Inanc, MD, Professor of Rheumatology, Department of Rheumatology, Faculty of Medicine, Istanbul University; G. Keser, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine, Ege University; N. Akkoc, MD, Professor of Rheumatology, Department of Rheumatology, School of Medicine
出版信息
J Rheumatol. 2015 Aug;42(8):1443-7. doi: 10.3899/jrheum.140817. Epub 2015 Jul 1.
OBJECTIVE
To assess the Indian Takayasu Clinical Activity Score (ITAS2010) in followup of Takayasu arteritis (TA).
METHODS
ITAS2010 forms were filled in prospectively (n = 144). Clinical activity was assessed with physician's global assessment (PGA) and criteria defined by Kerr, et al.
RESULTS
ITAS2010 was significantly higher in patients with active disease. Total agreement between ITAS2010 and PGA was 66.4%, and between ITAS2010 and Kerr, et al was 82.8%. During followup, 14 of 15 patients showing vascular progression with imaging were categorized as having inactive disease according to ITAS2010.
CONCLUSION
ITAS2010 was discriminatory for activity during the followup, but the agreement between PGA and ITAS2010 was moderate. Future work should include the incorporation of advanced vascular imaging and demonstration of ITAS2010 as a scalable measure and not simply a dichotomous measure of activity/flare versus remission.
目的
评估印度大动脉炎临床活动评分（ITAS2010）在大动脉炎（TA）随访中的应用。
方法
前瞻性填写ITAS2010表格（n = 144）。采用医生整体评估（PGA）以及Kerr等人定义的标准评估临床活动度。
结果
疾病活动期患者的ITAS2010评分显著更高。ITAS2010与PGA的总体一致性为66.4%，ITAS2010与Kerr等人标准的总体一致性为82.8%。在随访期间，15例经影像学检查显示血管病变进展的患者中，根据ITAS2010被归类为疾病非活动期的有14例。
结论
ITAS2010在随访期间对活动度具有鉴别能力，但PGA与ITAS2010之间的一致性为中等。未来的工作应包括纳入先进的血管成像技术，并证明ITAS2010是一种可扩展的测量方法，而不仅仅是活动/发作与缓解的二分法测量。
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