铜绿假单胞菌菌株WS136的基因组序列草图，WS136是从坏疽性脓皮病中分离出的一株具有高细胞毒性且携带ExoS的伤口菌株。
Draft Genome Sequence of Pseudomonas aeruginosa Strain WS136, a Highly Cytotoxic ExoS-Positive Wound Isolate Recovered from Pyoderma Gangrenosum.
作者信息
Arnold Martin, Wibberg Daniel, Blom Jochen, Schatschneider Sarah, Winkler Anika, Kutter Yvonne, Rückert Christian, Albersmeier Andreas, Albaum Stefan, Goesmann Alexander, Zange Sabine, Heesemann Jürgen, Pühler Alfred, Hogardt Michael, Vorhölter Frank-Jörg
机构信息
CeBiTec (Center for Biotechnology), Universität Bielefeld, Bielefeld, Germany.
Max von Pettenkofer-Institut, Ludwig-Maximilians-Universität, München, Germany.
出版信息
Genome Announc. 2015 Jul 2;3(4):e00680-15. doi: 10.1128/genomeA.00680-15.
Abstract
Pseudomonas aeruginosa is an opportunistic pathogen that typically infects patients with a compromised immune defense. Here, we present the improved 6.5-Mb draft genome of strain WS136, an ExoS-positive and ExoU-negative highly cytotoxic chronic wound isolate recovered from pyoderma gangrenosum of a patient who received bone marrow transplantation.
摘要
铜绿假单胞菌是一种机会致病菌，通常感染免疫防御功能受损的患者。在此，我们展示了菌株WS136改进后的650 kb草图基因组，该菌株是从一名接受骨髓移植患者的坏疽性脓皮病中分离出的、外毒素S阳性且外毒素U阴性的高细胞毒性慢性伤口分离株。
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