Department of Surgical Sciences, Vascular Surgery, Uppsala University, Uppsala, Sweden; Clinic for Cardiovascular Surgery, University Hospital, Zurich, Switzerland; Department of Surgery, Stockholm South Hospital, Stockholm, Sweden.
Department of Surgical Sciences, Vascular Surgery, Uppsala University, Uppsala, Sweden.
Eur J Vasc Endovasc Surg. 2015 Oct;50(4):460-5. doi: 10.1016/j.ejvs.2015.05.012. Epub 2015 Jul 2.
To analyze the early and long-term survival and re-intervention rate in patients undergoing TEVAR for blunt traumatic thoracic aortic injury.
This was a consecutive case series. Between the years 2001 and 2010, a total of 74 patients underwent TEVAR for blunt traumatic thoracic aortic injury at four tertiary referral centers, three in Sweden and one in Switzerland. The median age of the patients was 41 years, and 16% were women. Demographic, procedural, and outcome data were collected and reviewed retrospectively. The patients were followed up during 2013-2014.
Early (30 day) mortality was 9% (7 patients), with only two cases directly related to the aortic injury; in hospital mortality was 14% as three patients died during the primary hospital admission within the first 6 months. Most patients had sustained severe injuries to other organ systems, and among all in hospital deaths brain injury was the predominant cause. Five year survival in the whole group was 81%. Re-intervention was needed in 16% (12 patients) during the first year, half of them within the first month. Only one patient underwent re-intervention more than 1 year after the initial procedure. Infolding and partial stentgraft collapse was the reason for the secondary procedure in five of the 13 patients; in three it occurred within 3 weeks of the acute TEVAR.
TEVAR allows rapid and effective therapy in trauma patients with blunt aortic injury. The outcome is dependent on the severity of the concomitant injuries. The treatment is durable during the first decade after the procedure, but even longer follow up is needed to determine the impact of TEVAR in young patients on the degenerative changes that take place in the aging aorta.
分析接受胸主动脉腔内修复术(TEVAR)治疗钝性胸主动脉损伤患者的早期和长期生存及再干预率。
这是一项连续病例系列研究。在 2001 年至 2010 年期间,4 家三级转诊中心(瑞典 3 家,瑞士 1 家)共对 74 例钝性胸主动脉损伤患者进行了 TEVAR。患者的中位年龄为 41 岁,16%为女性。收集并回顾性分析了人口统计学、手术过程和结果数据。患者在 2013-2014 年期间接受了随访。
早期(30 天)死亡率为 9%(7 例),仅有 2 例直接与主动脉损伤有关;住院期间死亡率为 14%,有 3 例患者在最初 6 个月内的住院期间死亡。大多数患者有其他器官系统的严重损伤,所有住院死亡病例中,颅脑损伤是主要原因。全组患者 5 年生存率为 81%。在第 1 年中有 16%(12 例)需要再次干预,其中一半在第 1 个月内。仅有 1 例患者在初次手术后 1 年以上再次接受介入治疗。13 例患者中有 5 例因折叠和部分支架内陷而行二次手术,其中 3 例发生在急性 TEVAR 后 3 周内。
TEVAR 可使钝性主动脉损伤患者迅速有效地接受治疗。结果取决于伴随损伤的严重程度。在术后的第一个十年中,治疗效果持久,但仍需要更长时间的随访来确定 TEVAR 在年轻患者中的应用对老年主动脉退行性改变的影响。