Jones D G
University of Otago, Dunedin, New Zealand.
J Med Ethics. 1989 Dec;15(4):173-8, 185. doi: 10.1136/jme.15.4.173.
The concept of brain birth has assumed a position of some significance in discussions on the status of the human embryo and on the point in embryonic development prior to which experimental procedures may be undertaken on human embryos. This paper reviews previous discussions of this concept, which have placed brain birth at various points between 12 days' and 20 weeks' gestation and which have emphasised the symmetry of brain birth and brain death. Major developmental features of brain development are outlined, including the gradualness with which new features generally appear, and also the electroencephalogram (EEG) characteristics of premature infants. From this it is concluded that, if the concept of brain birth is a valid one, it should be placed at 24-28 weeks' gestation. More importantly, it is concluded that the differences between brain development and brain death throw doubt on the concept itself.
脑诞生的概念在关于人类胚胎地位以及在胚胎发育过程中可对人类胚胎进行实验操作的时间点的讨论中占据了一定重要地位。本文回顾了此前关于这一概念的讨论,这些讨论将脑诞生置于妊娠12天至20周之间的不同时间点,并强调了脑诞生与脑死亡的对称性。概述了脑发育的主要发育特征,包括新特征通常出现的渐进性,以及早产儿的脑电图(EEG)特征。由此得出结论,如果脑诞生的概念是有效的,那么它应被置于妊娠24 - 28周。更重要的是,得出的结论是脑发育与脑死亡之间的差异使这一概念本身受到质疑。