Donesky DorAnne
University of California, San Francisco, California.
Curr Opin Support Palliat Care. 2015 Sep;9(3):212-6. doi: 10.1097/SPC.0000000000000153.
The purpose of this review is to synthesize the current literature on classification and management of acute breathlessness that occurs in patients who are living with chronic refractory breathlessness related to cancer, cardiopulmonary, or neuromuscular disease.
In the context of chronic refractory breathlessness, acute breathlessness can be classified as either episodic breathlessness or breathlessness crisis. Episodic breathlessness is characterized by the severity, duration, and predictability of the symptom, and by the presence or absence of a trigger such as exertion, emotion, or an environmental factor. Breathlessness crisis is more sustained, occurs at rest, and overwhelms the patient's and caregivers' coping abilities, similar to the nontriggered unpredictable types of episodic breathlessness. Treatment of acute breathlessness focuses on alleviating the episode as quickly as possible without escalating medical intervention that may not be consistent with the patient's treatment preferences.
Attention to breathlessness in the published literature has increased exponentially in the past two decades. The challenge is now to translate the research findings into relief of symptoms, suffering, and distress in those who suffer from acute and chronic breathlessness because of chronic illness.
本综述旨在综合当前关于癌症、心肺疾病或神经肌肉疾病相关慢性难治性呼吸困难患者出现的急性呼吸困难的分类和管理的文献。
在慢性难治性呼吸困难的背景下,急性呼吸困难可分为发作性呼吸困难或呼吸困难危象。发作性呼吸困难的特征在于症状的严重程度、持续时间和可预测性,以及是否存在诸如运动、情绪或环境因素等触发因素。呼吸困难危象更为持久,发生于静息状态,且超出患者及照护者的应对能力,类似于无触发因素的不可预测型发作性呼吸困难。急性呼吸困难的治疗重点是尽快缓解发作,同时避免增加可能与患者治疗偏好不符的医疗干预。
在过去二十年中,已发表文献对呼吸困难的关注呈指数级增长。现在的挑战是将研究结果转化为缓解因慢性病而患有急性和慢性呼吸困难者的症状、痛苦和困扰。