Thirumala Parthasarathy, Frederickson Andrew M, Balzer Jeffrey, Crammond Donald, Habeych Miguel E, Chang Yue-Fang, Sekula Raymond F
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
J Neurosurg. 2015 Oct;123(4):1059-64. doi: 10.3171/2014.12.JNS141699. Epub 2015 Jul 10.
Microvascular decompression is a safe and effective procedure to treat hemifacial spasm, but the operation poses some risk to the patient's hearing. While severe sensorineural hearing loss across all frequencies occurs at a low rate in experienced hands, a recent study suggests that as many as one-half of patients who undergo this procedure may experience ipsilateral high-frequency hearing loss (HFHL), and as many as one-quarter may experience contralateral HFHL. While it has been suggested that drill-related noise may account for this finding, this study was designed to examine the effect of a number of techniques designed to protect the vestibulocochlear nerve from operative manipulation on the incidence of HFHL.
Pure-tone audiometry was performed both preoperatively and postoperatively on 67 patients who underwent microvascular decompression for hemifacial spasm during the study period. A change of greater than 10 dB at either 4 kHz or 8 kHz was considered to be HFHL. Additionally, the authors analyzed intraoperative brainstem auditory evoked potentials from this patient cohort.
The incidence of ipsilateral HFHL in this cohort was 7.4%, while the incidence of contralateral HFHL was 4.5%. One patient (1.5%; also included in the HFHL group) experienced an ipsilateral nonserviceable hearing loss.
The reduced incidence of HFHL in this study suggests that technical modifications including performing the procedure without the use of fixed retraction may greatly reduce, but not eliminate, the occurrence of HFHL following microvascular decompression for hemifacial spasm.
微血管减压术是治疗面肌痉挛的一种安全有效的手术方法,但该手术对患者听力存在一定风险。虽然在经验丰富的医生手中,全频率严重感音神经性听力损失的发生率较低,但最近的一项研究表明,接受该手术的患者中多达一半可能会出现同侧高频听力损失(HFHL),多达四分之一可能会出现对侧HFHL。虽然有人认为钻孔相关噪声可能是这一发现的原因,但本研究旨在探讨多种旨在保护前庭蜗神经免受手术操作影响的技术对HFHL发生率的影响。
在研究期间,对67例接受微血管减压术治疗面肌痉挛的患者进行术前和术后纯音听力测试。在4kHz或8kHz时变化大于10dB被认为是HFHL。此外,作者分析了该患者队列的术中脑干听觉诱发电位。
该队列中同侧HFHL的发生率为7.4%,而对侧HFHL的发生率为4.5%。1例患者(1.5%;也包含在HFHL组中)出现同侧失用性听力损失。
本研究中HFHL发生率的降低表明,包括不使用固定牵开器进行手术在内的技术改进可能会大大降低,但不能消除面肌痉挛微血管减压术后HFHL的发生。