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15名因食物气传变应原导致哮喘的男孩在一年中的两个时期(冬季和夏季)因体力活动引发的“迟发性”梗阻

["Late" obstruction induced by physical exertion in 15 boys with asthma caused by food aeroallergens in 2 periods of the year (winter and summer)].

作者信息

De Luca L, Berni Canani M

机构信息

I. Divisione di Pediatria e Servizio, Fisiopatologia Respiratoria e Allergologica, Ospedale Santobono, Napoli, Italia.

出版信息

Pediatr Med Chir. 1989 Jul-Aug;11(4):385-7.

PMID:2616342
Abstract

The aim of this study was the observation of the presence of the "late" phase of obstruction after free run in subjects responsive either to aeoallergens either to food allergens but with withdrawal of food allergens from diet in comparison with control group of children which did not have the food allergens exclusion. The study was executed in February and in June in the same children's group having the purpose to observe the variation of this phase in June with a great pollination of graminacee. The results showed the presence of a late phase of obstruction of magnitude similar to the quick phase which begun from III to VII h. but was no greater than -20% FEV1 fall. The control group showed in many children the fall of -20% FEV1 fall. The group of children responsive to the graminacee with food allergen's exclusion showed in June a greater obstructive late phase in comparison to February but the obstruction never was greater than -20% FEV1 fall.

摘要

本研究的目的是观察在自由跑步后,对气传过敏原或食物过敏原产生反应但已从饮食中去除食物过敏原的受试者中“迟发”阻塞期的存在情况,并与未排除食物过敏原的儿童对照组进行比较。该研究于2月和6月在同一儿童组中进行,目的是观察在6月禾本科植物大量授粉时这一阶段的变化。结果显示存在一个阻塞迟发期,其程度与速发期相似,始于3至7小时,但FEV1下降不超过20%。对照组在许多儿童中显示FEV1下降20%。在6月,排除食物过敏原且对禾本科植物有反应的儿童组与2月相比,阻塞迟发期更大,但阻塞从未超过FEV1下降20%。

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