如何命名儿童膀胱乳头状肿瘤：移行细胞癌还是低恶性潜能乳头状尿路上皮肿瘤？
How to Name Papillary Tumors of the Bladder in Children: Transitional Cell Carcinoma or Papillary Urothelial Neoplasm of Low Malignant Potential?
作者信息
Umlauf Volker N, Coerdt Wiltrud, Leuschner Ivo, Schröder Annette, Stein Raimund, Beetz Rolf
机构信息
Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics, University Hospital RWTH Aachen, Aachen, Germany; Division of Pediatric Nephrology, Department of Pediatrics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Institute of Human Genetics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
出版信息
Urology. 2015 Aug;86(2):379-83. doi: 10.1016/j.urology.2015.04.021. Epub 2015 Jul 10.
Urinary bladder malignancies are uncommon in children. Approximately 80 children with papillary carcinoma have been described to date, presenting as papillary neoplasms of both low grade and low stage. On the basis of the 1973 World Health Organization classification, tumors were classified as transitional cell carcinoma of the urinary bladder (TCCB). Owing to more detailed histologic criteria, this term has been replaced by papillary urothelial neoplasm of low malignant potential and low-grade carcinoma of the urinary bladder in the World Health Organization-International Society of Urologic Pathology consensus classification system of urothelial neoplasms 2004. Nevertheless, TCCB still remains a common term in contemporary literature. Thus, the differences between papillary urothelial neoplasm of low malignant potential, low-grade carcinoma of the urinary bladder, and TCCB will be illustrated by means of 4 examples of pediatric patients with papillary tumors.
膀胱恶性肿瘤在儿童中并不常见。迄今为止，大约已有80例乳头状癌患儿被报道，表现为低级别、低分期的乳头状肿瘤。根据1973年世界卫生组织的分类，这些肿瘤被归类为膀胱移行细胞癌（TCCB）。由于组织学标准更加细化，在世界卫生组织-国际泌尿病理学会2004年尿路上皮肿瘤共识分类系统中，这一术语已被低恶性潜能乳头状尿路上皮肿瘤和膀胱低级别癌所取代。然而，TCCB在当代文献中仍然是一个常用术语。因此，将通过4例乳头状肿瘤患儿的病例来说明低恶性潜能乳头状尿路上皮肿瘤、膀胱低级别癌和TCCB之间的差异。
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