Luo Biao, Liao Fei, Hu Yanchun, Liu X I, He Yajun, Wu Lei, Tan Hui, Luo Lijuan, Zhou Yancheng, Mo Quan, Deng Junliang, Wei Yahui
Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China ; Qiandongnan Prefectural Center for Animal Disease Control and Prevention, Kaili, Guizhou 556000, P.R. China.
Exp Ther Med. 2015 Jul;10(1):247-250. doi: 10.3892/etm.2015.2503. Epub 2015 May 19.
The aim of the present study was to investigate the acaricidal activity of . An extract was prepared by refluxing with ethanol and steam distillation, and its toxic effect was tested against . The data from the toxicity tests were analyzed using a complementary log-log (CLL) model. The ethanol extract exhibited strong acaricidal activity against these mites; at a concentration of 2 g/ml it killed all within 2 h and at 1 g/ml it killed all within 6 h. Similarly, 2, 1, 0.5 and 0.25 g/ml concentrations of the extract had strong toxicity against , with median lethal time (LT) values of 0.716, 1.741, 2.968 and 4.838 h, respectively. The median lethal concentration (LC) values were 1.388, 0.624, 0.310 and 0.213 g/ml for mite in 1, 2, 4 and 6 h, respectively. The results indicate that the extract has strong acaricidal activity and may be exploited as a novel treatment for the effective control of acariasis in animals.
本研究的目的是调查……的杀螨活性。通过乙醇回流和水蒸气蒸馏制备提取物,并测试其对……的毒性作用。使用互补对数-对数(CLL)模型分析毒性试验数据。乙醇提取物对这些螨虫表现出很强的杀螨活性;浓度为2克/毫升时,在2小时内杀死了所有……,浓度为1克/毫升时,在6小时内杀死了所有……。同样,提取物浓度为2、1、0.5和0.25克/毫升时对……具有很强的毒性,中位致死时间(LT)值分别为0.716、1.741、2.968和4.838小时。对于……螨虫,在1、2、4和6小时时的中位致死浓度(LC)值分别为1.388、0.624、0.310和0.213克/毫升。结果表明,……提取物具有很强的杀螨活性,可作为一种新型治疗方法用于有效控制动物螨病。