Cheng Chi-Liang, Liu Nai-Jen, Tang Jui-Hsiang, Yu Ming-Chin, Tsui Yi-Ning, Hsu Fang-Yu, Lee Ching-Song, Lin Cheng-Hui
Division of Gastroenterology, Department of Medicine, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
Endosc Int Open. 2015 Jun;3(3):E216-22. doi: 10.1055/s-0034-1391480. Epub 2015 May 6.
Data on double-balloon enteroscopy (DBE)-assisted endoscopic retrograde cholangiopancreatogrphy (ERCP) in patients with Billroth II gastrectomy and the use of endoscopic papillary large-balloon dilation (EPLBD) for the removal of common bile duct stones in Billroth II anatomy are limited. The aims of the study were to evaluate the success of DBE-assisted ERCP in patients with Billroth II gastrectomy and examine the efficacy of EPLBD ( ≥ 10 mm) for the removal of common bile duct stones.
A total of 77 patients with Billroth II gastrectomy in whom standard ERCP had failed underwent DBE-assisted ERCP. DBE success was defined as visualizing the papilla and ERCP success as completing the intended intervention. The clinical results of EPLBD for the removal of common bile duct stones were analyzed.
DBE was successful in 73 of 77 patients (95 %), and ERCP success was achieved in 67 of these 73 (92 %). Therefore, the rate of successful DBE-assisted ERCP was 87 % (67 of a total of 77 patients). The reasons for ERCP failure (n = 10) included tumor obstruction (n = 2), adhesion obstruction (n = 2), failed cannulation (n = 3), failed stone removal (n = 2), and bowel perforation (n = 1). Overall DBE-assisted ERCP complications occurred in 5 of 77 patients (6.5 %). A total of 48 patients (34 male, mean age 75.5 years) with common bile duct stones underwent EPLBD. Complete stone removal in the first session was accomplished in 36 patients (75 %); mechanical lithotripsy was required in 1 patient. EPLBD-related mild perforation occurred in 2 patients (4 %). No acute pancreatitis occurred.
DBE permits therapeutic ERCP in patients who have a difficult Billroth II gastrectomy with a high success rate and acceptable complication rates. EPLBD is effective and safe for the removal of common bile duct stones in patients with Billroth II anatomy.
关于毕Ⅱ式胃切除术后患者行双气囊小肠镜(DBE)辅助内镜逆行胰胆管造影(ERCP)以及在内镜下乳头大球囊扩张术(EPLBD,球囊直径≥10mm)用于毕Ⅱ式解剖结构患者胆总管结石取出方面的数据有限。本研究旨在评估毕Ⅱ式胃切除术后患者行DBE辅助ERCP的成功率,并探讨EPLBD(≥10mm)在取出胆总管结石方面的疗效。
共有77例行毕Ⅱ式胃切除术且标准ERCP失败的患者接受了DBE辅助ERCP。DBE成功定义为观察到乳头,ERCP成功定义为完成预期干预。分析了EPLBD取出胆总管结石的临床结果。
77例患者中有73例DBE成功(95%),这73例中有67例ERCP成功(92%)。因此,DBE辅助ERCP的成功率为87%(77例患者中的67例)。ERCP失败的原因(n = 10)包括肿瘤梗阻(n = 2)、粘连梗阻(n = 2)、插管失败(n = 3)、结石取出失败(n = 2)和肠穿孔(n = 1)。77例患者中有5例发生了总体DBE辅助ERCP并发症(6.5%)。共有48例胆总管结石患者(男性34例,平均年龄75.5岁)接受了EPLBD。36例患者(75%)在首次操作时结石完全取出;1例患者需要机械碎石。2例患者(4%)发生了与EPLBD相关的轻度穿孔。未发生急性胰腺炎。
DBE使毕Ⅱ式胃切除困难的患者能够成功进行治疗性ERCP,成功率高且并发症发生率可接受。EPLBD用于毕Ⅱ式解剖结构患者取出胆总管结石有效且安全。