[与HIV感染相关的神经系统疾病]

[Neurological disorders associated with HIV-infection].

作者信息

Evzelman M A, Snimschikova I A, Koroleva L Ya, Kamchatnov P R

机构信息

Orel State University, Orel.

Pirogov Russian National Research Medical University, Moscow.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(3):89-93. doi: 10.17116/jnevro20151153189-93.

DOI:10.17116/jnevro20151153189-93

PMID:26171483

Abstract

HIV-infection is a common intractable disease which is often concomitant with nervous system lesions. We considered the main mechanisms of nervous tissue lesions in AIDS, in particular, those caused by opportunistic infections. The current data about the problem of neurological disorders in patients with HIV-infection, pathogenesis characteristics, HIV-infection complications, diagnosis and treatment strategy were analyzed. Neurologic complications of HIV-infection is a valid reason for a decision to start a highly active antiretroviral treatment.

摘要

HIV感染是一种常见的难治性疾病，常伴有神经系统病变。我们探讨了艾滋病中神经组织病变的主要机制，特别是由机会性感染引起的病变。分析了有关HIV感染患者神经功能障碍问题、发病机制特点、HIV感染并发症、诊断和治疗策略的现有数据。HIV感染的神经并发症是决定开始高效抗逆转录病毒治疗的一个合理理由。