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急诊小肠梗阻中腹腔镜与开腹肠切除术的比较:国家外科质量改进计划数据库分析

Laparoscopic Versus Open Bowel Resection in Emergency Small Bowel Obstruction: Analysis of the National Surgical Quality Improvement Program Database.

作者信息

Sharma Rohit, Reddy Subhash, Thoman David, Grotts Jonathan, Ferrigno Lisa

机构信息

1 Santa Barbara Cottage Hospital , Santa Barbara, California.

2 Cleveland Clinic , Cleveland, Ohio.

出版信息

J Laparoendosc Adv Surg Tech A. 2015 Aug;25(8):625-30. doi: 10.1089/lap.2014.0446. Epub 2015 Jul 14.

Abstract

BACKGROUND

Small bowel obstruction (SBO) is commonly encountered by surgeons and has traditionally been handled via an open approach, especially when small bowel resection (SBR) is indicated, although recent series have shown improved outcomes with a laparoscopic approach. In this retrospective study, we sought to evaluate outcomes and identify risk factors for adverse events after emergency SBR for SBO with an emphasis on surgical approach.

MATERIALS AND METHODS

In this retrospective review using American College of Surgeons National Surgical Quality Improvement Program data, 1750 patients were identified who had emergency SBR with the principal diagnosis of SBO from 2006 to 2011. Mortality and postoperative adverse events were evaluated.

RESULTS

Of 1750 patients who had emergency SBR, 51 (2.9%) had laparoscopic bowel resection (LBR). There was no difference in surgery duration (open bowel resection [OBR] versus LBR, 100 minutes versus 92 minutes; P=.38). Compared with the LBR group, the OBR group had a higher rate of baseline cardiac comorbidities and postoperative complications, and their length of stay was longer (10 versus 8 days; P<.001). Using multivariate analysis, perioperative variables of age >70 years, pulmonary, renal, neurological, and cardiac comorbidities, preoperative sepsis, steroid use, and body mass index of <30 kg/m(2) were associated with increased odds of mortality. OBR was associated with overall increased odds of morbidity (2.8; P=.003) and postoperative wound (2.9; P=.018) and respiratory (6.5; P=.011) infections.

CONCLUSIONS

LBR was associated with equivalent operative time, shorter length of stay, less morbidity, and equivalent mortality compared with OBR. Although therapy for SBO secondary to adhesive disease remains controversial, our study shows numerous benefits to the laparoscopic approach to SBOs and thus should be considered a first-line treatment option for the management of this common surgical problem.

摘要

背景

小肠梗阻(SBO)是外科医生常见的病症,传统上通过开放手术处理,特别是在需要进行小肠切除术(SBR)时,尽管最近的系列研究表明腹腔镜手术方法能改善预后。在这项回顾性研究中,我们旨在评估急诊SBR治疗SBO后的预后情况,并确定不良事件的危险因素,重点关注手术方式。

材料与方法

在这项使用美国外科医师学会国家外科质量改进计划数据的回顾性研究中,确定了2006年至2011年期间因SBO作为主要诊断而接受急诊SBR的1750例患者。评估了死亡率和术后不良事件。

结果

在1750例接受急诊SBR的患者中,51例(2.9%)接受了腹腔镜肠切除术(LBR)。手术时间无差异(开放肠切除术[OBR]与LBR,分别为100分钟和92分钟;P = 0.38)。与LBR组相比,OBR组基线心脏合并症和术后并发症发生率更高,住院时间更长(分别为10天和8天;P < 0.001)。通过多变量分析,年龄>70岁、肺部、肾脏、神经和心脏合并症、术前脓毒症、使用类固醇以及体重指数<30 kg/m²等围手术期变量与死亡几率增加相关。OBR与总体发病率增加几率(2.8;P = 0.003)、术后伤口感染(2.9;P = 0.018)和肺部感染(6.5;P = 0.011)相关。

结论

与OBR相比,LBR手术时间相当、住院时间更短、发病率更低且死亡率相当。尽管粘连性疾病继发SBO的治疗仍存在争议,但我们的研究表明腹腔镜治疗SBO有诸多益处,因此应被视为处理这一常见外科问题的一线治疗选择。

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