Kennedy David J, Engel Andrew, Kreiner D Scott, Nampiaparampil Devi, Duszynski Belinda, MacVicar John
Department of Orthopaedics, Stanford University, Redwood City, California, USA.
Affordable Pain Management, Chicago, Illinois, USA.
Pain Med. 2015 Aug;16(8):1500-18. doi: 10.1111/pme.12833. Epub 2015 Jul 14.
To assess the validity of fluoroscopically guided diagnostic intra-articular injections of local anesthetic and effectiveness of intra-articular steroid injections in treating sacroiliac joint (SIJ) pain.
Systematic review.
Ten reviewers independently assessed 45 publications on diagnostic validity or effectiveness of fluoroscopically guided intra-articular SIJ injections.
For diagnostic injections, the primary outcome was validity; for therapeutic injections, analgesia. Secondary outcomes were also described.
Of 45 articles reviewed, 39 yielded diagnostic data on physical exam findings, provocation tests, and SIJ injections for diagnosing SIJ pain, and 15 addressed therapeutic effectiveness. When confirmed by comparative local anesthetic blocks with a high degree of pain relief, no single physical exam maneuver predicts response to diagnostic injections. When at least three physical exam findings are present, sensitivity, and specificity increases significantly. The prevalence of SIJ pain is likely 20-30% among patients that have suspected SIJ pain based on history and physical examination. This estimate may be higher in certain subgroups such as the elderly and fusion patients. Two randomized controlled trials and multiple observational studies supported the effectiveness of therapeutic sacroiliac joint injections.
Based on this literature, it is unclear whether image-guided intra-articular diagnostic injections of local anesthetic predict positive responses to therapeutic agents. The overall quality of evidence is moderate for the effectiveness of therapeutic SIJ injections.
评估在荧光透视引导下进行关节内注射局部麻醉剂诊断骶髂关节(SIJ)疼痛的有效性,以及关节内注射类固醇治疗骶髂关节疼痛的有效性。
系统评价。
10名评价者独立评估了45篇关于荧光透视引导下关节内骶髂关节注射诊断有效性或治疗有效性的出版物。
对于诊断性注射,主要观察指标是有效性;对于治疗性注射,主要观察指标是镇痛效果。还描述了次要观察指标。
在纳入评价的45篇文章中,39篇提供了关于体格检查结果、激发试验和用于诊断骶髂关节疼痛的骶髂关节注射的诊断数据,15篇涉及治疗效果。当通过具有高度疼痛缓解效果的对比性局部麻醉阻滞得到证实时,没有单一的体格检查操作能够预测对诊断性注射的反应。当至少存在三项体格检查结果时,敏感性和特异性会显著增加。在根据病史和体格检查怀疑有骶髂关节疼痛的患者中,骶髂关节疼痛的患病率可能为20%至30%。在某些亚组中,如老年人和融合患者,这一估计值可能更高。两项随机对照试验和多项观察性研究支持了骶髂关节治疗性注射的有效性。
基于这些文献,尚不清楚影像引导下关节内注射局部麻醉剂是否能预测对治疗药物的阳性反应。关于骶髂关节治疗性注射有效性的证据总体质量中等。