Fuchs F, Senat M-V
Département de gynécologie-obstétrique, hôpital Bicêtre, AP-HP, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France; Université Paris-Sud, UMRS 1018, 94807 Villejuif, France.
J Gynecol Obstet Biol Reprod (Paris). 2015 Oct;44(8):760-70. doi: 10.1016/j.jgyn.2015.06.011. Epub 2015 Jul 14.
The literature confirms the interest of progesterone for prevention of preterm delivery in specific indications for patients carrying a singleton pregnancy. In contrast, randomized trials have shown no benefit using progesterone in the prevention of prematurity in twins and even an adverse effect.
文献证实,对于单胎妊娠患者的特定适应症,孕酮在预防早产方面具有重要意义。相比之下,随机试验表明,孕酮在预防双胎早产方面并无益处,甚至会产生不良影响。