[抗高血压治疗依从性评估]
[Assessment of adherence to antihypertensive therapy].
作者信息
Varleta Paola, Akel Carlos, Acevedo Mónica, Salinas Claudia, Pino Javier, Opazo Viviana, García Ana, Echegoyen Carolina, Rodríguez Daniel, Gramusset Lissette, León Sandra, Cofré Pedro, Hernández Hilda, Neira Patricia, Retamal Raquel, Petit Gloria, Moya Natalia
出版信息
Rev Med Chil. 2015 May;143(5):569-76. doi: 10.4067/S0034-98872015000500003.
BACKGROUND
Lack of adherence with medications is the main cause of antihypertensive treatment failure.
AIM
To assess adherence to antihypertensive drugs and its determinants.
MATERIAL AND METHODS
The Morinsky-Green questionnaire to determine treatment adherence was applied to 310 hypertensive patients from primary care centers, aged 60 ± 10 years (65% females) in treatment for 4 ± 1 months. Socio-demographic features, use of medications and quality of life using EQ5D questionnaire were also assessed.
RESULTS
Twenty percent of patients were diabetic and 19% were smokers. Fifty four percent were adherent to therapy. A higher age and being unemployed were associated with a higher compliance. The main reasons to justify the lack of adherence were forgetting to take the pills in 67% and adverse effects in 10%. Only diastolic pressure was lower in adherent patients, compared with their non-adherent counterparts (78 ± 12 and 81 ± 17 mmHg, respectively p < 0.01).
CONCLUSIONS
Only half of hypertensive patients comply with their antihypertensive therapy.
背景
不坚持服药是抗高血压治疗失败的主要原因。
目的
评估抗高血压药物的依从性及其决定因素。
材料与方法
对来自基层医疗中心的310例高血压患者应用Morinsky-Green问卷来确定治疗依从性，这些患者年龄为60±10岁（65%为女性），治疗时间为4±1个月。还评估了社会人口学特征、药物使用情况以及使用EQ5D问卷评估的生活质量。
结果
20%的患者患有糖尿病，19%的患者吸烟。54%的患者坚持治疗。年龄较大和失业与较高的依从性相关。不坚持服药的主要原因是67%的患者忘记服药，10%的患者是由于药物不良反应。与不依从的患者相比，依从患者的舒张压更低（分别为78±12 mmHg和81±17 mmHg，p<0.01）。
结论
只有一半的高血压患者坚持抗高血压治疗。
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