Suppr超能文献

头颈部癌游离组织移植术后30天再入院的患病率及患者层面的危险因素

Prevalence and Patient-Level Risk Factors for 30-Day Readmissions Following Free Tissue Transfer for Head and Neck Cancer.

作者信息

Offodile Anaeze C, Pathak Abraham, Wenger Julia, Orgill Dennis P, Guo Lifei

机构信息

Department of Plastic Surgery, Lahey Hospital & Medical Center, Burlington, Massachusetts.

Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.

出版信息

JAMA Otolaryngol Head Neck Surg. 2015 Sep;141(9):783-9. doi: 10.1001/jamaoto.2015.1323.

Abstract

IMPORTANCE

Hospital readmissions are a marker of surgical care delivery and quality that are progressively more scrutinized.

OBJECTIVE

To provide a comprehensive analysis of 30-day readmissions for patients with head and neck cancer who underwent free flap reconstruction to highlight the rate, causes, and associated patient risk factors.

DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort study at a single tertiary care academic institution. The study consisted of 249 patients who underwent microvascular reconstruction of a presumed head and neck oncologic defect from January 1, 2000, through June 30, 2014. Follow-up continued through July 30, 2014.

INTERVENTIONS

Microvascular reconstruction of an oncologic head and neck defect.

MAIN OUTCOMES AND MEASURES

Incidence of 30-day all-cause readmissions, patient risk factors, and readmission indications. Regression analyses were conducted to discern patient-level risk factors related to 30-day readmissions.

RESULTS

Among the 249 patients, the 30-day all-cause readmission rate was 14.5%, while the unplanned readmission rate was 11.6%. The most common reason for readmission was neck wound complications. Predictors of readmission following multivariable analysis were T4 pathologic stage (odds ratio [OR], 11.68; 95% CI, 1.37-99.81; P = .02) and having a tumor located in the oropharynx (OR, 4.64; 95% CI, 1.89-11.38; P = .001), hypopharynx (OR, 8.30; 95% CI, 1.52-45.24; P = .01), or larynx (OR, 10.97; 95% CI, 2.27-52.98; P = .003). Patients who were readmitted were more likely to experience neck wound complications (OR, 5.07; 95% CI, 1.31-19.57; P = .02) and undergo reoperation (OR, 47.20; 95% CI, 8.33-267.33; P < .001).

CONCLUSIONS AND RELEVANCE

In this study, advanced pathologic tumor staging and tumor location were associated with 30-day readmissions in patients with head and neck cancer who receive free flaps. Our results provide a benchmark for risk stratification that can be used in system-based practice improvements, health care cost savings, and postoperative patient counseling.

摘要

重要性

医院再入院是外科护理服务和质量的一个指标,且受到越来越多的严格审查。

目的

对接受游离皮瓣重建的头颈癌患者的30天再入院情况进行全面分析,以突出发生率、原因及相关患者风险因素。

设计、地点和参与者:在一家单一的三级医疗学术机构进行的回顾性队列研究。该研究纳入了2000年1月1日至2014年6月30日期间接受微血管重建以修复假定的头颈肿瘤缺损的249例患者。随访持续至2014年7月30日。

干预措施

对头颈肿瘤缺损进行微血管重建。

主要结局和指标

30天全因再入院发生率、患者风险因素及再入院指征。进行回归分析以识别与30天再入院相关的患者层面风险因素。

结果

在这249例患者中,30天全因再入院率为14.5%,而计划外再入院率为11.6%。再入院最常见的原因是颈部伤口并发症。多变量分析后,再入院的预测因素为T4病理分期(比值比[OR],11.68;95%置信区间[CI],1.37 - 99.81;P = 0.02)以及肿瘤位于口咽(OR,4.64;95% CI,1.89 - 11.38;P = 0.001)、下咽(OR,8.30;95% CI,1.52 - 45.24;P = 0.01)或喉(OR,10.97;95% CI,2.27 - 52.98;P = 0.003)。再入院的患者更有可能出现颈部伤口并发症(OR,5.07;95% CI,1.31 - 19.57;P = 0.02)并接受再次手术(OR,47.20;95% CI,8.33 - 267.33;P < 0.001)。

结论及相关性

在本研究中,晚期病理肿瘤分期和肿瘤位置与接受游离皮瓣的头颈癌患者的30天再入院相关。我们的结果为风险分层提供了一个基准,可用于基于系统的实践改进、医疗成本节约及术后患者咨询。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验