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1例Douglas陷凹内性腺外畸胎瘤及文献复习

A Case of Extragonadal Teratoma in the Pouch of Douglas and Literature Review.

作者信息

Kakuda Mamoru, Matsuzaki Shinya, Kobayashi Eiji, Yoshino Kiyoshi, Morii Eiichi, Kimura Tadashi

机构信息

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan.

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan.

出版信息

J Minim Invasive Gynecol. 2015 Nov-Dec;22(7):1311-7. doi: 10.1016/j.jmig.2015.07.008. Epub 2015 Jul 20.

Abstract

Mature cystic teratoma is a germ cell tumor of the ovaries and is often observed in clinical practice. However, extragonadal teratomas are rare tumors and have been reported outside the ovaries, (e.g., in the greater omentum). The mechanism underlying the development of extragonadal teratomas remains unknown. We encountered a case of extragonadal teratoma in the pouch of Douglas that appeared to be a parasitic dermoid cyst. From our experience and the literature review, we discuss the potential mechanism leading to the development of extragonadal teratomas. A 41-year-old nonpregnant woman was referred to our department due to myoma and anemia. A 4-cm asymptomatic mass in the pouch of Douglas was observed, and the patient was diagnosed with ovarian mature cystic teratoma. She underwent laparoscopic surgery, and intraoperative findings revealed that the fallopian tube was injured and torn, and a residual small ovary was observed in the left side of the ovary. A tumor measuring approximately 4 cm observed in the pouch of Douglas was extracted without rupturing. The tumor was diagnosed as a parasitic dermoid cyst by macroscopic and histopathological findings. Auto-amputation could be the underlying mechanism that leads to an isolated parasitic dermoid cyst in the pouch of Douglas.

摘要

成熟囊性畸胎瘤是一种卵巢生殖细胞肿瘤,在临床实践中较为常见。然而,性腺外畸胎瘤是罕见肿瘤,已报道其可发生于卵巢外(如大网膜)。性腺外畸胎瘤的发生机制尚不清楚。我们遇到一例发生于Douglas陷凹的性腺外畸胎瘤,似乎是一个寄生性皮样囊肿。结合我们的经验及文献复习,我们讨论了导致性腺外畸胎瘤发生的潜在机制。一名41岁未孕女性因肌瘤和贫血转诊至我科。在Douglas陷凹发现一个4厘米无症状肿物,患者被诊断为卵巢成熟囊性畸胎瘤。她接受了腹腔镜手术,术中发现输卵管受损并撕裂,在卵巢左侧观察到一个残留的小卵巢。在Douglas陷凹发现的一个约4厘米大小的肿瘤被完整取出未破裂。通过宏观和组织病理学检查结果,该肿瘤被诊断为寄生性皮样囊肿。自体截断可能是导致Douglas陷凹孤立性寄生性皮样囊肿的潜在机制。

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