Pentek Falk, Schulte Johannes H, Schweiger Bernd, Metzelder Martin, Schündeln Michael M
Department of Pediatric Hematology and Oncology, Kinderklinik III, Universitätsklinikum-Essen and the University of Duisburg-Essen, Essen, Germany.
Charité Universitätsmedizin, Department of Pediatrics, Division of Oncology and Hematology, Berlin, Germany.
Pediatr Blood Cancer. 2016 Jan;63(1):149-51. doi: 10.1002/pbc.25677. Epub 2015 Jul 23.
We report a 26-month-old female who developed port-site metastases of a neuroblastoma following minimally invasive thoracoscopic interventions. After diagnosis of an intrathoracic low-risk neuroblastoma and 6 months of observation, she developed respiratory problems. She subsequently underwent total resection of a locally progressive tumor via thoracoscopy. Six months later, she developed local relapse and subcutaneous metastases within the thoracic wall. These port-site metastases were most likely iatrogenic. After excision of metastases, the residual tumor responded well to salvage chemotherapy. The patient has remained in remission for over 4 years.
我们报告一名26个月大的女性,她在微创胸腔镜干预后发生了神经母细胞瘤的切口转移。在诊断为胸腔内低风险神经母细胞瘤并观察6个月后,她出现了呼吸问题。随后,她通过胸腔镜对局部进展性肿瘤进行了全切。6个月后,她出现了局部复发以及胸壁皮下转移。这些切口转移很可能是医源性的。在切除转移灶后,残留肿瘤对挽救性化疗反应良好。该患者已缓解超过4年。