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与开放转换相比,急性失败的血管内动脉瘤修复血管内转换为主动脉单髂动脉构型与更好的一年生存率相关。

Endovascular conversion into aorto-uniiliac configuration of acute failed endovascular aneurysm repair is associated with better one-year survival rates compared to open conversion.

作者信息

Prusa Alexander M, Wibmer Andreas G, Nolz Richard, Schoder Maria, Teufelsbauer Harald

机构信息

Department of Vascular Surgery, Medical University of Vienna, Austria.

Department of Biomedical Imaging and Image-guided Therapy, Division of Cardiovascular and Interventional Radiology, Medical University of Vienna, Austria.

出版信息

Surgeon. 2017 Jun;15(3):131-138. doi: 10.1016/j.surge.2015.06.007. Epub 2015 Jul 22.

Abstract

BACKGROUND

Open conversions (OC) due to failed endovascular repair of infrarenal abdominal aortic aneurysms (EVAR) are technically demanding because of preexisting prostheses and advanced aortic disease. This study evaluates the feasibility and outcomes of aorto-uniiliac endografting (AUI) as an alternative treatment option in acute failed EVAR.

METHODS

From March 1995 through February 2012, 26 patients underwent acute conversion of failed EVAR at our tertiary care university center. All data were prospectively entered in our institutional database. Outcomes included 30-day or in-hospital mortality, postoperative complications, and mid-term survival.

RESULTS

During the investigation period, a total of 692 patients received EVAR at our institution, while five of the 26 patients with acute conversion (19.2%) had an initial EVAR at an outlying institution and were referred for treatment. Therefore, our estimated institutional rate of acute conversions was 3% (21 of 692 EVAR). OC were performed in 14 patients (53.8%), while 12 patients underwent AUI (46.2%). An average time of 20.3 months (median: 18.6; interquartile range Q1-Q3: 0.0-38.6) elapsed between the initial EVAR and the acute conversion. All acute AUI conversion procedures were completed successfully. The 30-day mortality following acute conversions was 42.3% and since the use of AUI, it could be reduced to 33.3%. Kaplan-Meier estimates revealed a survival advantage for AUI at one year (p = 0.046), but the benefit was lost by mid-term follow-up (p = 0.103).

CONCLUSIONS

AUI for the treatment of acute failed EVAR represents a feasible and less invasive alternative to OC, and is associated with better one-year survival rates.

摘要

背景

由于肾下腹主动脉瘤腔内修复术(EVAR)失败而进行的开放转换术(OC)技术要求较高,这是因为存在先前植入的假体以及严重的主动脉疾病。本研究评估了主动脉单髂动脉内支架植入术(AUI)作为急性EVAR失败后的一种替代治疗方案的可行性和疗效。

方法

从1995年3月至2012年2月,26例患者在我们的三级大学医疗中心接受了急性EVAR失败后的转换手术。所有数据均前瞻性地录入我们的机构数据库。结果包括30天或住院死亡率、术后并发症以及中期生存率。

结果

在研究期间,我们机构共有692例患者接受了EVAR,其中26例急性转换患者中有5例(19.2%)最初在外地机构接受了EVAR,后来被转诊至我院接受治疗。因此,我们机构急性转换的估计发生率为3%(692例EVAR中的21例)。14例患者(53.8%)接受了OC,而12例患者接受了AUI(46.2%)。从最初的EVAR到急性转换的平均时间为20.3个月(中位数:18.6;四分位间距Q1-Q3:0.0-38.6)。所有急性AUI转换手术均成功完成。急性转换后的30天死亡率为42.3%,自采用AUI以来,死亡率可降至33.3%。Kaplan-Meier估计显示,AUI在1年时具有生存优势(p = 0.046),但在中期随访时这种优势消失了(p = 0.103)。

结论

AUI治疗急性EVAR失败是一种可行且侵入性较小的OC替代方案,并且与更好的1年生存率相关。

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