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急性肾损伤:远程缺血预处理能否预防急性肾损伤?

Acute kidney injury: Can remote ischaemic preconditioning prevent AKI?

作者信息

Zuk Anna, Bonventre Joseph V

机构信息

Renal Division and Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 4 Blackfan Circle, Boston, MA 02115, USA.

出版信息

Nat Rev Nephrol. 2015 Sep;11(9):512-3. doi: 10.1038/nrneph.2015.119. Epub 2015 Jul 28.

Abstract

A randomized multicentre controlled study of 240 cardiac surgery patients at high risk of acute kidney injury (AKI) has demonstrated that remote ischaemic preconditioning can reduce the rate of AKI and requirement for renal replacement therapy. These findings suggest this procedure could be a promising therapeutic option for this high-risk patient group.

摘要

一项针对240名急性肾损伤(AKI)高危心脏手术患者的随机多中心对照研究表明,远程缺血预处理可降低AKI发生率及肾脏替代治疗需求。这些发现表明,该程序可能是这一高危患者群体的一种有前景的治疗选择。

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