胺在离子液体中比在普通分子溶剂中是更强的碱吗？胺的精确碱度标度。

Is Amine a Stronger Base in Ionic Liquid Than in Common Molecular Solvent? An Accurate Basicity Scale of Amines.

作者信息

Mao Chong, Wang Zhen, Ji Pengju, Cheng Jin-Pei

机构信息

†Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing 100084, China.

‡State Key Laboratory of Elemento-organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China.

出版信息

J Org Chem. 2015 Aug 21;80(16):8384-9. doi: 10.1021/acs.joc.5b01200. Epub 2015 Aug 12.

DOI:10.1021/acs.joc.5b01200

PMID:26218631

Abstract

The equilibrium basicities of 21 frequently used amines in two room-temperature ionic liquids (RTILs) were measured precisely. The standard deviation was much superior to that sparsely reported elsewhere. The data comparisons revealed that amines are stronger bases in ionic ligquids than in DMSO and water but weaker base than in acetonitrile (AN). Interestingly, regression analyses demonstrate that the basicity scales obtained in two RTILs correlate well with that in AN but not with those in water and DMSO.

摘要

精确测量了21种常用胺类在两种室温离子液体（RTILs）中的平衡碱度。其标准偏差比其他地方稀疏报道的要优越得多。数据比较表明，胺类在离子液体中的碱性比在二甲基亚砜（DMSO）和水中强，但比在乙腈（AN）中弱。有趣的是，回归分析表明，在两种RTILs中获得的碱度标度与在AN中的碱度标度相关性良好，但与在水和DMSO中的碱度标度不相关。