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急诊科患者淋病奈瑟菌和沙眼衣原体感染病例的治疗

Treatment of Cases of Neisseria gonorrhoeae and Chlamydia trachomatis in Emergency Department Patients.

作者信息

Schechter-Perkins Elissa M, Jenkins Dareema, White Laura F, Mitchell Patricia M

机构信息

From the *Department of Emergency Medicine, Boston University School of Medicine, Boston, MA; †Wellstar Cobb Hospital, Atlanta, GA; and ‡Department of Biostatistics, Boston University School of Public Health, Boston MA.

出版信息

Sex Transm Dis. 2015 Jul;42(7):353-7. doi: 10.1097/OLQ.0000000000000299.

Abstract

BACKGROUND

The aim of this study was to determine the proportion of patients treated appropriately, both presumptively in the emergency department (ED), and at follow-up, among those patients who ultimately tested positive for either Neisseria gonorrhoeae (NG) or Chlamydia trachomatis (CT). Secondary aims were to characterize patients who received appropriate presumptive antibiotic treatment of both NG and CT at the time of ED visit and to compare them to patients who did not receive appropriate presumptive therapy.

METHODS

A retrospective chart review was performed on 500 patients randomly chosen from those that had positive NG or CT test results performed in the ED between January 10 and June 11. The Center for Disease Control and Prevention 2010 STD Treatment Guidelines were used to determine appropriate antibiotics.

RESULTS

We found 54% (95% confidence interval [CI], 49%-58%) of patients received appropriate antibiotics at ED visit and an additional 31% (95% CI, 27%-35%) were treated at our medical center on follow-up. Fifteen percent did not have documented treatment. Providers presumptively treated 46% (95% CI, 42%-50%) of patients studied with antibiotics appropriate for both NG and CT. The presence of behavioral risk factors and, for males, the presence of genital symptoms were the only factors independently associated with presumptive ED treatment.

CONCLUSIONS

Among patients diagnosed as having NG or CT in this ED, a portion were not documented to ever receive appropriate antibiotics, although a call-back system is in place. Presumptive treatment was not commonly used in this ED but may be necessary given the high number of patients who never got treated.

摘要

背景

本研究的目的是确定最终淋病奈瑟菌(NG)或沙眼衣原体(CT)检测呈阳性的患者中,在急诊科(ED)接受初步合理治疗以及在后续随访中接受合理治疗的患者比例。次要目的是对在急诊就诊时接受NG和CT合理初步抗生素治疗的患者进行特征描述,并将他们与未接受合理初步治疗的患者进行比较。

方法

对1月10日至6月11日期间在急诊科进行NG或CT检测结果呈阳性的患者中随机抽取的500例患者进行回顾性病历审查。采用疾病控制与预防中心2010年性传播疾病治疗指南来确定合适的抗生素。

结果

我们发现54%(95%置信区间[CI],49%-58%)的患者在急诊就诊时接受了合适的抗生素治疗,另外31%(95%CI,27%-35%)在后续随访中在我们的医疗中心接受了治疗。15%的患者没有记录在案的治疗情况。医疗服务提供者对46%(95%CI,42%-50%)的研究患者采用了适合NG和CT的抗生素进行初步治疗。行为危险因素的存在以及男性生殖器症状的存在是与急诊初步治疗独立相关的唯一因素。

结论

在该急诊科诊断为患有NG或CT的患者中,尽管有回访系统,但仍有一部分患者没有记录显示曾接受过合适的抗生素治疗。该急诊科不常用初步治疗,但鉴于大量患者从未接受治疗,初步治疗可能是必要的。

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