Babalola Olufemi Emmanuel
Rachel Eye Center, Abuja, Nigeria ; Department of Ophthalmology, College of Health Sciences, Bingham University, New Karu, Nigeria.
Clin Ophthalmol. 2015 Jul 20;9:1347-51. doi: 10.2147/OPTH.S82678. eCollection 2015.
The term micropulse laser trabeculoplasty suggests that only a fraction of the laser power is applied to the trabeculum to effect pressure lowering. It has not yet been exclusively used in Negroes, and we wish to report on our experience in Nigerian patients.
The study design is a retrospective chart review of our patients at the Rachel Eye Center in Abuja. The 810 diode Optos FastPulse laser was used to apply 34 cycles of treatment to 30 eyes of 16 individuals. Patients were selected based on the failure of maximal medical therapy. One patient had two extra rounds of treatment, while two patients were treated in only one eye. The pressure change at 1 hour after the treatment was analyzed. Patients were followed up for a mean period of 160 days with continuous monitoring of pressure changes. Patients' original therapy was not disturbed.
Postlaser immediate drop in intraocular pressure (IOP) averaged 3.2 mmHg (CI 1.6-4.7, P<0.0001) representing 17.2% drop from baseline prelaser IOP. The drop in IOP was sustained over varying periods, from a few weeks to several months. There was a temporary spike in three instances. No serious side effects were noted.
Micropulse diode laser trabeculoplasty is a useful adjunct in the management of open-angle glaucoma in Nigerians. This corroborates the findings of other researchers in western populations.
微脉冲激光小梁成形术这一术语表明,仅将一部分激光能量应用于小梁以降低眼压。该技术尚未专门应用于黑人患者,我们希望报告我们在尼日利亚患者中的经验。
本研究设计为对位于阿布贾的瑞秋眼科中心的患者进行回顾性病历审查。使用810二极管Optos快速脉冲激光对16名个体的30只眼睛进行34个周期的治疗。根据最大药物治疗失败来选择患者。一名患者额外接受了两轮治疗,两名患者仅一只眼睛接受了治疗。分析治疗后1小时的眼压变化。对患者进行平均160天的随访,持续监测眼压变化。患者的原治疗方案未受干扰。
激光治疗后眼压立即下降,平均下降3.2 mmHg(可信区间1.6 - 4.7,P<0.0001),相对于激光治疗前的基线眼压下降了17.2%。眼压下降在不同时间段内持续,从几周至几个月不等。有3例出现暂时性眼压升高。未观察到严重副作用。
微脉冲二极管激光小梁成形术是尼日利亚开角型青光眼治疗中的一种有用辅助手段。这证实了西方人群中其他研究人员的发现。