Oesterwitz H, Fritsch W, Schneider W, Kreuschner H
Abteilung für experimentelle Organtransplantation der Klinik für Urologie, Bereichs Medizin, (Charité) der Humboldt-Universität zu Berlin.
Z Exp Chir Transplant Kunstliche Organe. 1989;22(6):337-41.
A machine for continuous hypothermic pulsatile perfusion preservation of rat kidneys is described in detail. The use of longwave ultraviolet irradiation during hypothermic pulsatile kidney perfusion using Euro-Collins solution containing 8-MOP did not prolong graft survival compared with untreated controls. Systemic application of 8-MOP to the kidney donor may be necessary for effective action of the combined photochemical treatment as a method of immunoalteration.
详细描述了一种用于大鼠肾脏连续低温脉动灌注保存的机器。在使用含8-甲氧基补骨脂素的欧洲柯林斯溶液进行低温脉动肾脏灌注期间,与未处理的对照组相比,长波紫外线照射并未延长移植物存活时间。作为一种免疫改变方法,联合光化学疗法要有效发挥作用,可能需要对肾脏供体全身应用8-甲氧基补骨脂素。