Aduba Donald C, Overlin Jefferson W, Frierson Chad D, Bowlin Gary L, Yang Hu
Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA.
Department of Chemistry, Virginia Commonwealth University, Richmond, VA 23284, USA.
Mater Sci Eng C Mater Biol Appl. 2015 Nov 1;56:189-94. doi: 10.1016/j.msec.2015.06.025. Epub 2015 Jun 14.
Polyamidoamine (PAMAM) dendrimers have emerged as an important class of nanostructured materials and have found a broad range of applications. There is also an ongoing effort to synthesize higher-complexity structures using PAMAM dendrimers as enabling building blocks. Herein, we report for the first time the fabrication of electrospun nanocomposite fibers composed of dendrimer derivatives, namely PEGylated PAMAM dendrimers, blended with a small amount of high-molecular-weight polyethylene oxide (PEO). Morphological features and mechanical properties of the resulting dendrimer fiber mats were assessed.
聚酰胺-胺(PAMAM)树枝状大分子已成为一类重要的纳米结构材料,并已得到广泛应用。人们也在不断努力,以PAMAM树枝状大分子为基础构建单元来合成更高复杂度的结构。在此,我们首次报道了由树枝状大分子衍生物,即聚乙二醇化的PAMAM树枝状大分子,与少量高分子量聚环氧乙烷(PEO)混合而成的电纺纳米复合纤维的制备。对所得树枝状大分子纤维毡的形态特征和力学性能进行了评估。