大数据：大型前瞻性随机试验在未来会过时吗？

Big data: Are large prospective randomized trials obsolete in the future?

作者信息

Hudis Clifford A

机构信息

Memorial Sloan Kettering Cancer Center, United States; Weill Cornell Medical College, United States.

出版信息

Breast. 2015 Nov;24 Suppl 2:S15-8. doi: 10.1016/j.breast.2015.07.005.

DOI:10.1016/j.breast.2015.07.005

PMID:26255742

Abstract

Big data represents a new opportunity to increase our understanding of cancer care as it is practiced globally and to improve it through the refinement of clinic guidelines and the identification of knowledge gaps. Here we review the historical approach to evidence development (randomized clinical trials), some of their limitations, and the complementary role that big data analytics may play.

摘要

大数据为我们提供了一个新机会，使我们能更好地了解全球范围内的癌症治疗情况，并通过完善临床指南和识别知识差距来改善癌症治疗。在此，我们回顾了循证医学发展的历史方法（随机临床试验）、其一些局限性，以及大数据分析可能发挥的补充作用。