Lupi F R, Gentile L, Gabriele D, Mazzulla S, Baldino N, de Cindio B
Department of Information, Modeling, Electronics and System Engineering (D.I.M.E.S.), University of Calabria, Via P. Bucci, Cubo 39C, I-87036 Rende, CS, Italy.
Department of Chemistry and Chemical Technologies, University of Calabria, Via P. Bucci, Cubo 14D, I-87036 Rende, CS, Italy.
J Colloid Interface Sci. 2015 Dec 1;459:70-78. doi: 10.1016/j.jcis.2015.08.013. Epub 2015 Aug 5.
Bigels are biphasic systems produced with an organogel (or oleogel) and a hydrogel mixed together at high shear rates. These systems are promising for different uses, among them the formulation of new cosmetic matrices for cosmetic agents delivery is under investigation. In the present paper, a common cosmetic formulation for skin care was enriched with increasing fractions of monoglycerides of fatty acids/olive oil organogels, in order to understand the rheology and the microstructure of these systems. Small amplitude oscillation tests, NMR-self diffusion analysis, contrast phase microscopy and electric conductivity confirmed that the addition of the organogel caused a microstructural change of the starting material, which turned from O/W to a more complex system where, probably, a matrix-in-matrix structure is present at the highest fractions of added organogel.
双凝胶是通过在高剪切速率下将有机凝胶(或油凝胶)和水凝胶混合在一起而制成的双相体系。这些体系具有多种潜在用途,其中用于递送化妆品成分的新型化妆品基质配方正在研究中。在本文中,一种常见的皮肤护理化妆品配方中添加了越来越多的脂肪酸单甘油酯/橄榄油有机凝胶,以了解这些体系的流变学和微观结构。小振幅振荡测试、核磁共振自扩散分析、相差显微镜和电导率证实,添加有机凝胶导致起始材料的微观结构发生变化,从水包油体系转变为更复杂的体系,在添加有机凝胶的最高比例下,可能存在一种基质内基质结构。