Toomey C, Leahy S, McCreesh K, Coote S, Jakeman P
4i Centre for Interventions in Infection, Inflammation and Immunity, Graduate Entry Medical School, University of Limerick, Limerick, Ireland.
Department of Clinical Therapies, University of Limerick, Limerick, Ireland.
Ir J Med Sci. 2016 May;185(2):537-44. doi: 10.1007/s11845-015-1338-x. Epub 2015 Aug 12.
Regional distribution of adiposity and lean tissue mass are predictors of health risk that cannot be defined by body mass index but can be attained by dual-energy X-ray absorptiometry (DXA). Age and sex-related adult ranges of whole-body and regional adiposity and lean tissue are not available for Irish men and women.
The aim of this study was to construct a DXA-based body composition profile of Irish adults, focusing on age- and sex-related difference in total and regional adiposity and lean tissue mass.
The study population comprised a convenience sample of 1606 participants, aged 18-81 years participating in the University of Limerick Body Composition study. Data were analysed to construct stature-normalised indices of body fat mass (BFMI), site-specific visceral adiposity, lean tissue mass (LTMI) and appendicular lean tissue mass (ALTMI).
Compared to the young adult (18-29 years), BFMI was higher in women (p < 0.001) but plateaued in men aged >50 years. For men, age-related difference in LTMI was not evident but ALTMI was significantly lower in those >50 years. For women, there was evidence of significantly lower LTMI with advancing age and, similar to men, significantly lower ALTMI in those >50 years.
These data provide an insight into the age-related anthropometric phenotype of Irish adults. Centile data have been constructed that provide informative data of the age and sex-specific range of adiposity and lean tissue mass. These data may assist in identification of those at risk of aberrant, body composition-related disease.
肥胖和瘦组织质量的区域分布是健康风险的预测指标,这些指标无法通过体重指数来定义,但可以通过双能X线吸收法(DXA)获得。爱尔兰男性和女性尚无与年龄和性别相关的全身及局部肥胖和瘦组织的成人参考范围。
本研究旨在构建基于DXA的爱尔兰成年人身体成分概况,重点关注全身及局部肥胖和瘦组织质量的年龄和性别差异。
研究人群为1606名年龄在18 - 81岁之间参与利默里克大学身体成分研究的便利样本。对数据进行分析,以构建身高标准化的体脂质量指数(BFMI)、特定部位内脏脂肪、瘦组织质量指数(LTMI)和附属瘦组织质量指数(ALTMI)。
与年轻成年人(18 - 29岁)相比,女性的BFMI更高(p < 0.001),但50岁以上男性的BFMI趋于平稳。对于男性,LTMI的年龄相关差异不明显,但50岁以上男性的ALTMI显著较低。对于女性,有证据表明随着年龄增长LTMI显著降低,并且与男性类似,50岁以上女性的ALTMI也显著较低。
这些数据为爱尔兰成年人与年龄相关的人体测量学表型提供了见解。已构建百分位数数据,提供了肥胖和瘦组织质量的年龄和性别特异性范围的信息数据。这些数据可能有助于识别那些有身体成分相关异常疾病风险的人群。