来自乌檀的三种新的同分异构吲哚生物碱。
Three New Isomeric Indole Alkaloids from Nauclea officinalis.
作者信息
Wang Hai-Yang, Wang Ru-Xia, Zhao Yan-Xia, Liu Ke, Wang Feng-Ling, Sun Jing-Yong
机构信息
Key Laboratory of Rare and Uncommon Diseases, Institute of Materia Medica, Shandong Academy of Medical Sciences, Ji'nan, 250062, Shandong, P. R. China, (phone: +86-531-82919963; fax: +86-531-82919963).
Shandong Academy of Medical Sciences Graduate Education Center, Ji'nan, 250062, Shandong, P. R. China.
出版信息
Chem Biodivers. 2015 Aug;12(8):1256-62. doi: 10.1002/cbdv.201400289.
Three new isomeric monoterpene indole alkaloids, naucleofficines I-III (1-3, resp.) were isolated from the stems (with bark) of Nauclea officinalis. Their structures were elucidated on the basis of spectroscopic methods and single-crystal diffraction analyses. The cytotoxic activities of 1-3 against human colon cancer, human gastric cancer, and human hepatoma cells were also investigated.
从乌檀的茎（带树皮）中分离出三种新的同分异构单萜吲哚生物碱，分别为乌檀辛碱I - III（分别为1 - 3）。基于光谱方法和单晶衍射分析对它们的结构进行了阐明。还研究了1 - 3对人结肠癌细胞、人胃癌细胞和人肝癌细胞的细胞毒性活性。
Zotero 插件