用于脆性角膜综合征的角膜交联术。
Corneal Cross-Linking for Brittle Cornea Syndrome.
作者信息
Kaufmann Claude, Schubiger Gregor, Thiel Michael A
机构信息
*Department of Ophthalmology, Lucerne Cantonal Hospital, Lucerne, Switzerland; and †Ethics Committee for Research on Humans, Department of Health, Lucerne, Switzerland.
出版信息
Cornea. 2015 Oct;34(10):1326-8. doi: 10.1097/ICO.0000000000000577.
PURPOSE
To describe corneal cross-linking (CXL) as a treatment option for brittle cornea syndrome (BCS).
METHODS
Case report.
RESULTS
Ethical decision making enabled bilateral sequential transepithelial CXL in an 11-year-old girl with BCS. Postoperative courses were uneventful with a bilateral stromal demarcation line, unchanged corneal transparency, constant endothelial cell density, and stable topography 2 years after intervention.
CONCLUSIONS
Modified CXL can safely be performed in patients with BCS. Ethical review may be helpful for interventions deviating from standard practice.
目的
描述角膜交联术（CXL）作为脆性角膜综合征（BCS）的一种治疗选择。
方法
病例报告。
结果
通过伦理决策，对一名患有BCS的11岁女孩实施了双侧序贯上皮下CXL。术后过程顺利，干预2年后出现双侧基质分界线，角膜透明度未变，内皮细胞密度恒定，地形图稳定。
结论
改良的CXL可安全地应用于BCS患者。伦理审查可能有助于偏离标准做法的干预措施。
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