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DaPeCa-2:阴茎癌快速临床路径的实施缩短了等待时间并加速了诊断过程——丹麦一家三级转诊中心的前后对比研究

DaPeCa-2: Implementation of fast-track clinical pathways for penile cancer shortens waiting time and accelerates the diagnostic process--A comparative before-and-after study in a tertiary referral centre in Denmark.

作者信息

Jakobsen Jakob Kristian, Jensen Jørgen Bjerggaard

机构信息

a Department of Urology, Aarhus University Hospital , Aarhus, Denmark.

出版信息

Scand J Urol. 2016;50(1):80-7. doi: 10.3109/21681805.2015.1077472. Epub 2015 Aug 27.

Abstract

OBJECTIVE

The aim of this study was to examine the feasibility and impact of a fast-track referral pathway on clinical time intervals in penile cancer.

MATERIALS AND METHODS

This observational study from a tertiary referral centre included 263 patients diagnosed before and after the introduction of an intervention to reduce clinical time intervals, the Cancer Patient Pathway (CPP). The CPP included fast-track referral and set time-frames for units participating in cancer diagnosis and treatment, and was introduced for penile cancer in Denmark on 1 January 2009. Median time intervals (in calendar days) with interquartile range were the main outcome measure.

RESULTS

A trend towards reduction was observed in all clinical time intervals, with a statistically significant reduction in the system interval (p = 0.01) and tertiary centre interval (p < 0.0001). The proportion of patients treated within the maximum accepted time-frame of 37 days after referral steadily increased after implementation of the CPP. In particular, unjustified waiting time was reduced significantly. This was mainly achieved through pre-booking of appointments and diagnostic time slots by a dedicated clinical coordinator.

CONCLUSIONS

To the authors' knowledge, this is the first study examining the feasibility and impact of an intervention to reduce clinical time intervals in penile cancer. The Danish CPP was successful in reducing system and tertiary centre intervals. Future interventions need to address the long patient interval. Longer follow-up is needed to study the impact of CPP on mortality.

摘要

目的

本研究旨在探讨快速转诊途径在阴茎癌临床时间间隔方面的可行性及影响。

材料与方法

这项来自三级转诊中心的观察性研究纳入了263例在引入一项旨在缩短临床时间间隔的干预措施(癌症患者路径,CPP)前后被诊断出阴茎癌的患者。CPP包括快速转诊以及为参与癌症诊断和治疗的单位设定时间框架,并于2009年1月1日在丹麦引入用于阴茎癌。主要结局指标是四分位间距的中位时间间隔(以日历日计)。

结果

在所有临床时间间隔中均观察到缩短趋势,系统间隔(p = 0.01)和三级中心间隔(p < 0.0001)有统计学显著缩短。在实施CPP后,在转诊后37天这一最大可接受时间框架内接受治疗的患者比例稳步上升。特别是,不合理等待时间显著减少。这主要是通过由一名专门的临床协调员预先安排预约和诊断时段来实现的。

结论

据作者所知,这是第一项研究减少阴茎癌临床时间间隔干预措施的可行性及影响的研究。丹麦的CPP成功缩短了系统间隔和三级中心间隔。未来的干预措施需要解决患者间隔时间长的问题。需要更长时间的随访来研究CPP对死亡率的影响。

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