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人类心脏房室瓣的发育:对巴黎胚胎学藏品的重新审视

Atrioventricular valves development in human heart: the Paris embryological collection revisited.

作者信息

Mandarim-de-Lacerda C A

机构信息

Department of Anatomy, State University of Rio de Janeiro (UERJ), Brazil.

出版信息

Gegenbaurs Morphol Jahrb. 1989;135(6):947-55.

PMID:2628147
Abstract

29 human embryos staging from stage 15 to stage 23 (post-somitic period, collection of the UER Biomedicale des Saints-Péres, Université René Descartes Paris V) have been studied. The most important morphological events of the atrioventricular valves development have been reinvestigated and photographed. This is a complementary information about cardiac development analysing this french collection of human embryos (Mandarim-de-Lacerda, in press). At stage 15, we can observe the gelatinous reticulum well organized when cardiac valves will become established; progressively the fused endocardial cushions and right and left lateral cushions encircle the atrioventricular channels indicating the site of the tricuspid valves. These cushions, however, have a temporary influence being replaced gradually by atrial and ventricular myocardium. At stage 23, the heart presents a complete atrioventricular valvular structure.

摘要

对29个人类胚胎(发育阶段从第15期至第23期,处于体节形成后期,取自巴黎第五大学勒内·笛卡尔大学圣佩雷斯生物医学中心)进行了研究。重新研究并拍摄了房室瓣发育过程中最重要的形态学事件。这是分析这批法国人类胚胎样本(Mandarim-de-Lacerda,即将发表)时关于心脏发育的补充信息。在第15期,可以观察到当心脏瓣膜开始形成时,凝胶状网状结构组织良好;融合的心内膜垫以及左右外侧垫逐渐环绕房室通道,指示三尖瓣的位置。然而,这些垫子只有暂时的影响,逐渐被心房和心室心肌所取代。在第23期,心脏呈现出完整的房室瓣膜结构。

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