别嘌醇诱发的药物超敏反应伴嗜酸性粒细胞增多和系统症状综合征

Allopurinol Induced DRESS Syndrome.

作者信息

Pawar Pritesh, Gupta Vishal Anand, Karnik N D, Vaidya Meghna, Khopkar Uday

出版信息

J Assoc Physicians India. 2014 Nov;62(11):63-5.

Abstract

A 45 years old female on allopurinol for 3 months presented with itching, rash, facial oedema and eosinophilia with hepatic and renal dysfunction. Skin biopsy revealed interface dermatitis, suggesting the diagnosis of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome.

摘要

一名45岁女性服用别嘌醇3个月后出现瘙痒、皮疹、面部水肿、嗜酸性粒细胞增多以及肝肾功能不全。皮肤活检显示界面性皮炎，提示诊断为药物超敏反应伴嗜酸性粒细胞增多和全身症状（DRESS）综合征。